An integrated approach to dissecting and manipulating hepatic immune cell interactions
Underpinned by cutting-edge research techniques:
10-12 colour flow cytometry including MHC/peptide multimers for virus-specific cells
Flow cytometric and bead sorting of cell subsets;Immunofluoresecence of liver sections (including using TCR-like mAb to identify MHC/peptide complexes);
Image-stream analysis of cellular interactions;Functional analyses of cellular interactions (between immune cells and between immune and liver-resident cells);
Isolation and expansion of primary human liver resident cells including stellate cells for in vitro modeling of fibrosis;
Transduction and expansion of T cells with HBV-specific T cell receptors; Use of lentiviral vectors for gene modification;
Close
