Our current research focuses on the following main areas:
- Dissecting virus-host interactions that support successful HIV replication in T cells and understanding what makes a T cell permissive for HIV-1.
- Determining how HIV-1 reprograms T cells during infection and the implications for viral persistence and reservoir formation.
- Determining how SARS-CoV-2 VOCs have evolved to better suppress and evade human innate immune sensing and antiviral restriction factors.
- Evaluating antiviral therapeutics and inhibitors.
We have teamed up with the Towers’ lab to study SARS-CoV-2 and its interaction with host cells, read more about our research here:
The Jolly Lab is funded by the Wellcome Trust.