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Jolly Lab

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Jolly Lab

We aim to understand the cell biology of HIV-1 infection and spread between T cells. Dissecting the molecular details of how these processes work will provide greater insight into HIV-1 pathogenesis and inform future antiviral strategies.

Our current research focuses on four main areas:

  • Characterising virus-host interactions that support successful HIV replication in T cells
  • Dissecting the molecular determinants and regulators of cell-cell spread at virological synapses
  • Investigating how viral proteins are trafficked in infected cells and how virus assembly is coordinated
  • Evaluating antiviral therapeutics and inhibitors

       

       The Jolly Lab is funded by the Wellcome Trust.

       

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