Jolly Lab


Jolly Lab

We aim to understand the cell biology of HIV-1 infection and spread between T cells. Dissecting the molecular details of how these processes work will provide greater insight into HIV-1 pathogenesis and inform future antiviral strategies.

Our current research focuses on four main areas:

  • Characterising virus-host interactions that support successful HIV replication in T cells
  • Dissecting the molecular determinants and regulators of cell-cell spread at virological synapses
  • Investigating how viral proteins are trafficked in infected cells and how virus assembly is coordinated
  • Evaluating antiviral therapeutics and inhibitors

      We have teamed up with the Towers’ lab to study SARS-CoV-2 and its interaction with host cells, read more about our research here


       The Jolly Lab is funded by the Wellcome Trust.