Grants as principal applicant since 2000
2013-2016
Rosetrees Trust. Investigation of the role of chemokine signalling in retinal endothelial cells and its contribution to the development of retinal inflammatory conditions.
£107,208
2012-2013
University College London Business (UCLB), Proof of Concept Fund. (with S. Moss). The role of leucine-rich alpha-2-gycoprotein 1 (Lrg1) in cancer growth and metastasis.
£50,000
2011-2014
Fight for Sight (with S. Nourshargh). Molecular determinants of regional leukocyte traffic through the retinal vascular plexus.
£169,875
2011-2014
Rosetrees Trust/Impact studentship. The role of leucine-rich alpha-2-gycoprotein 1 in regulating retinal inflammatory disease.
£117,253 (£54,000 Rosetrees/£63,253 Impact)
2011-2014
Medical Research Council Developmental Pathway Funding Scheme (with S. Moss and J. Bainbridge). Development of a therapeutic antibody for a novel angiogenic target.
£759,418
2010-2013
Medical Research Council (with S. Moss and J. Bainbridge)
The role of leucine-rich alpha-2-glycoprotein in retinal vascular development and disease
£697,488
2010-2013
The Wellcome Trust (with S. Moss and J. Bainbridge)
The role of the apelin/APJ pathway in retinal vascular development and pathology
£295,334
2010-2013
The Wellcome Trust
Investigation of endothelial cell ICAM-1 signalling pathways and their role in controlling lymphocyte migration to the CNS
£290,139
2008-2010
Rosetrees Trust/Fight for Sight
Identifying new therapeutic targets and developing new treatments for retinal disease
£57,600
2007-2010
Moulton Charitable Foundation & Multiple Sclerosis Trials Collaboration (with V.Calder)
Immunomodulatory effect of long-term statin treatment in patients with secondary progressive multiple sclerosis
£126,483
2006-2009
Guide Dogs for the Blind Association (with P. Coffey and S. Moss)
Trans-differentiation of the human retinal pigment epithelial cell line ARPE-19 towards a photoreceptor phenotype: A potential cell for retinal repair
£162,970
2006-2009
Medical Research Council (with P. Turowski)
G-protein receptor signalling in CNS endothelial cells and its role in supporting lymphocyte migration
£460,000
2005-2010
The Lowy Medical Research Institute (Programme grant with S. Moss)
Vascular and RPE anomalies in idiopathic juxtafoveal telangiectasia
£881,000
2005-2009
European Union FP6 (with S. Moss)
Host retinal response to cellular therapy
£200,000
2002-2008
The Wellcome Trust (Programme Grant)
Investigation of endothelial mechanisms involved in facilitating leukocyte migration into the CNS
£701,829
2004-2007
Medical Research Council (with F. Fitzke, D. Keegan, J. Sinden and S. Moss)
Development of immortalised human foetal retinal progenitor stem cell lines for the treatment of retinal degeneration
£315,268
2004-2006
Merck Sharpe & Dohme (with P. Adamson and P. Turowski)
Development of immortalised rat brain endothelial cell lines
£131,930
2002-2005
The Multiple Sclerosis Society (with P. Adamson and D.Baker)
Therapeutic potential of pharmacological inhibition of brain endothelial cell signalling pathways controlling leukocyte migration into the CNS
£149,801
2000-2009
Joint Infrastructure Fund (Lead applicant with co-applicants S. Moss, P. Adamson, R. Ali, A. Bird, F. Fitzke, P. Khaw, P. Luthert and A. Webster)
Centre for the identification and development of novel treatment strategies for ocular disease
£9,200,000
2000-2003
The Wellcome Trust (with P. Coffey and R. Lund)
RPE transplantation in the RCS rat
£388,845
1998-2001
The Multiple Sclerosis Society (with P. Adamson)
Investigation of brain endothelial cell mechanisms controlling monocyte migration into the CNS: Identification of potential therapeutic targets
£128,601
1998-2000
ANVAR- (Demande d’aide a l’innovation. Grant from French Government) (with P. Couraud and P. Adamson)
Utilisation de lignées de cellules épithéliales pigmentaires rétiniennes en thérapie génique cellulaire de la dégénérescence maculaire liée à l’âge
4,000,000 FF (£400,000)
1997-2002
Neurotech S.A. (Programme grant with P. Adamson and R. Lund)
In vitro manufacture and in vivo assessment of immortalised human RPE cells and stealth RPE cells
£790,000