Research Fellow working in van der Spuy Lab

Job details

The key duties and responsibilities of the role will be to lead a project investigating gene replacement therapy for the treatment of a devastating blinding disease in children, Leber’s congenital amaurosis (LCA), caused by mutations in the AIPL1 gene. Three-dimensional human retinal organoids will be used to model the disease and test the efficacy of adeno associated virus (AAV)-mediated gene replacement to rescue the disease phenotype.  

The appointment will be funded until 31 Jan 2023 in the first instance.

Key requirements

It is essential to hold a doctoral degree in a relevant subject area. Strong technical and analytical skills are required, and advanced expertise in molecular and cell biology is essential. Expertise in iPSC culture and maintenance is desirable. The ability to lead a research project with a considerable degree of independence, and to work within tight deadlines is required, with a proven track record of contributing to the publication of journal articles and presenting at conferences. Active participation and contribution to laboratory meetings and wider collaborative communication will be required, in addition to a commitment to undertake training and the ability to learn new skills required for meeting the demands of the post.

Further details

If you have any queries regarding the vacancy please contact Dr Jacqueline van der Spuy.

If you have any queries regarding the application process please email hr.ioo@ucl.ac.uk.

Closing date

2 November 2021

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