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Bloomsbury Institute for Intensive Care Medicine

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Funding

2007-2010   

British Heart Foundation Project Grant (M Singer with L Clapp)  Regulation of vascular KATP channels in sepsis

2007-2012   

NIHR Research for Patient Benefit (RfPB) programme (M Singer and G Bellingan with M Grocott, P Meade, M Mythen, A Oshowa) RCT of the utility of Cardiopulmonary Exercise (CPX) testing for preoperative risk stratification to guide perioperative care and thereby reduce postoperative morbidity.

2008-2011   

Wellcome Trust Seeding Drug Discovery Award (M Singer with J Leiper, S Caddick, N MacDonald) Dimethylarginine dimethylaminohydrolase-1 inhibition in sepsis.

2009-2014    

Health Foundation and Academy of Medical Sciences Clinician Scientist Fellowship Award for Dr G Ackland Cellular and humoral mechanisms associated with improving surgical outcomes.

2008-2011   

European Commission (M Singer with Dr G Bertolini, Dr F Brunkhorst and others)

PROSAFE - PROmoting patient SAFEty and quality improvement in critical care

2009-2013   

MRC Industrial Collaborative studentship for Dr N Ekbal [£83,910] Continuous monitoring of the adequacy of organ perfusion using NADH fluorescence

2009-2012   

Wellcome Clinical Training Fellowship for Dr S Harris Do measures of duration and trajectory of illness refine definitions of sepsis phenotypes, and the criteria used to time triage to Intensive Care?

2010-2014    

NIHR Health Technology Assessment Programme (M Singer with K Rowan, D Harrison, et al) Protocolised Management In Sepsis (ProMISe): a multicentre, randomised controlled trial of the clinical and cost-effectiveness of early protocolised resuscitation for emerging septic shock

2009-2012   

NIHR Clinical Doctoral Research Fellowship for  C Black The feasibility and predictive value of monitoring exercise capacity in patients recovering from critical illness in intensive care.

2011-2014    

Wellcome Trust-NIHR Health Innovation Challenge Fund Award (M Singer, with Dr A Obeid, Prof S Morris) Tissue oxygen monitoring for detecting impending shock states and guiding therapy in the critically ill and those at high-risk.

2011-2014   

MRC Clinical Training Fellowship for Dr S Saeed The role of mitochondrial biogenesis in muscle function recovery in critical illness

2011-2014   

Wellcome Clinical Training Fellowship for Dr N Arulkumaran The P2X7 receptor and sepsis-induced acute kidney injury

2012-2016    

NIHR Efficacy and Mechanism Evaluation Programme Award (M Singer with A Gordon, D Ashby, D McAuley, R Orme and G Perkins) An efficacy and mechanism evaluation study of Levosimendan for the Prevention of Acute oRgan Dysfunction in Sepsis (LeoPARDS)

2013-2017   

European Union FP7 Grant (G Bellingan with others) CD73 in Acute Lung Injury

2014-2017    

MRC Developmental Pathway Funding (DPFS) Award  (M Singer, with CE Cooper, B Reeder et al) Engineering a new generation of blood substitutes