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2022

List of Whitehall II publications by Whitehall II researchers, ordered alphabetically by first author. This list includes consortia papers. 

  • Development and validation of a model to predict incident chronic liver disease in the general population: The CLivD score. Åberg F, Luukkonen PK, But A, Salomaa V, Britton A, Petersen KM, Bojesen SE, Balling M, Nordestgaard BG, Puukka P, Männistö S, Lundqvist A, Perola M, Jula A, Färkkilä M. J Hepatol. 77(2):302-311. 2022 (PMID: 35271949)
  • Association between age at onset of multimorbidity and incidence of dementia: 30 year follow-up in Whitehall II prospective cohort study. Ben Hassen C, Fayosse A, Landré B, Raggi M, Bloomberg M, Sabia S, Singh-Manoux A. BMJ. 376:e068005. 2022 (PMID: 35110302)
  • Metabolomic profiles predict individual multidisease outcomes. Buergel T, Steinfeldt J, Ruyoga G, Pietzner M, Bizzarri D, Vojinovic D, Upmeier Zu Belzen J, Loock L, Kittner P, Christmann L, Hollmann N, Strangalies H, Braunger JM, Wild B, Chiesa ST, Spranger J, Klostermann F, van den Akker EB, Trompet S, Mooijaart SP, Sattar N, Jukema JW, Lavrijssen B, Kavousi M, Ghanbari M, Ikram MA, Slagboom E, Kivimaki M, Langenberg C, Deanfield J, Eils R, Landmesser U. Nat Med. 28(11):2309-2320. 2022 (PMID: 36138150)
  • Proteomic signatures for identification of impaired glucose tolerance. Carrasco-Zanini J, Pietzner M, Lindbohm JV, Wheeler E, Oerton E, Kerrison N, Simpson M, Westacott M, Drolet D, Kivimaki M, Ostroff R, Williams SA, Wareham NJ, Langenberg C. Nat Med. 28(11):2293-2300. 2022 (PMID: 36357677)
  • Individual Barriers to an Active Lifestyle at Older Ages Among Whitehall II Study Participants After 20 Years of Follow-up. Chen M, Yerramalla MS, van Hees VT, Bloomberg M, Landré B, Fayosse A, Benadjaoud MA, Sabia S. JAMA Netw Open. 5(4):e226379. 2022 (PMID: 35389501)
  • Trajectories of alcohol consumption in relation to all-cause mortality in patients with cardiovascular disease: a 35-year prospective cohort study. Ding C, O'Neill D, Britton A. Addiction. 117(7):1920-1930. 2022 (PMID: 35188300)
  • Trajectories of alcohol consumption up to 30 years before and after the diagnosis of cardiovascular diseases: a longitudinal case-control study of 12 502 participants. Ding C, O'Neill D, Britton A. J Epidemiol Community Health. 76:497-504. 2022 (PMID: 34965970)
  • Overweight, obesity, and individual symptoms of depression: A multicohort study with replication in UK Biobank. Frank P, Jokela M, Batty GD, Lassale C, Steptoe A, Kivimäki M. Brain Behav Immun. 105:192-200. 2022 (PMID: 35853559)
  • Global, regional, and national burden of diseases and injuries for adults 70 years and older: systematic analysis for the Global Burden of Disease 2019 Study. GBD 2019 Ageing Collaborators. BMJ 10;376:e068208. 2022 (PMID: 35273014)
  • Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019. GBD 2019 Dementia Forecasting Collaborators. Lancet Public Health. 7(2):e105-e125. 2022 (PMID: 34998485)
  • Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020. GBD 2020 Alcohol Collaborators. Lancet. 400(10347):185-235. 2022 (PMID: 35843246)
  • Association of cerebral small vessel disease burden with brain structure and cognitive and vascular risk trajectories in mid-to-late life. Jansen MG, Griffanti L, Mackay CE, Anatürk M, Melazzini L, Lange AG, Filippini N, Zsoldos E, Wiegertjes K, Leeuw FE, Singh-Manoux A, Kivimäki M, Ebmeier KP, Suri S. J Cereb Blood Flow Metab. 42(4):600-612. 2022 (PMID: 34610763)
  • Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis. Kanoni S, Graham SE, Wang Y, Surakka I, Ramdas S, Zhu X, Clarke SL, Bhatti KF, Vedantam S, Winkler TW, Locke AE, Marouli E ett al. Genome Biol. 23(1):268. 2022 (PMID: 36575460)
  • Health conditions linked to heightened risk of Alzheimer's disease. Kivimäki M, Livingston G. Lancet Digit Health. 4(3):e150-e151. 2022 (PMID: 35216747)
  • Association of Major Surgical Admissions With Quality of Life: 19-Year Follow-up of the Whitehall II Longitudinal Prospective Cohort Study. Krause BM, Manning HJ, Sabia S, Singh-Manoux A, Sanders RD. JAMA Surg. 26:e217132. 2022 (PMID: 35080594)
  • Association of physical activity, sedentary behaviour, and daylight exposure with sleep in an ageing population: findings from the Whitehall accelerometer sub-study. Le Cornu Q, Chen M, van Hees V, Léger D, Fayosse A, Yerramalla MS, Sabia S. Int J Behav Nutr Phys Act. 19(1):144. 2022 (PMID: 36494722)
  • Immune system-wide Mendelian randomization and triangulation analyses support autoimmunity as a modifiable component in dementia-causing diseases. Lindbohm JV, Mars N, Sipilä PN, Singh-Manoux A, Runz H, FinnGen, Livingston G, Seshadri S, Xavier R, Hingorani AD, Ripatti S, Kivimäki M. Nat Aging. 2;10, 956–972 (2022) 
  • Plasma proteins, cognitive decline, and 20-year risk of dementia in the Whitehall II and Atherosclerosis Risk in Communities studies. Lindbohm JV, Mars N, Walker KA, Singh-Manoux A, Livingston G, Brunner EJ, Sipilä PN, Saksela K, Ferrie JE, Lovering RC, Williams SA, Hingorani AD, Gottesman RF, Zetterberg H, Kivimäki M. Alzheimers Dement. 18(4):612-624. 2022 (PMID: 34338426).
  • Prevalence of type 2 diabetes in psychiatric disorders: an umbrella review with meta-analysis of 245 observational studies from 32 systematic reviews. Lindekilde N, Scheuer SH, Rutters F, Knudsen L, Lasgaard M, Rubin KH, Henriksen JE, Kivimäki M, Andersen GS, Pouwer F. Diabetologia. 65(3):440-456. 2022 (PMID: 34841451)
  • Association of Metabolic Syndrome With Incident Dementia: Role of Number and Age at Measurement of Components in a 28-Year Follow-up of the Whitehall II Cohort Study. Machado-Fragua MD, Fayosse A, Yerramalla MS, van Sloten TT, Tabak AG, Kivimaki M, Sabia S, Singh-Manoux A. Diabetes Care. 45(9):2127-2135. (PMID: 35819815)
  • Circulating serum metabolites as predictors of dementia: a machine learning approach in a 21-year follow-up of the Whitehall II cohort study. Machado-Fragua MD, Landré B, Chen M, Fayosse A, Dugravot A, Kivimaki M, Sabia S, Singh-Manoux A. BMC Med. 20(1):334. 2022 (PMID: 36163029)
  • Associations between exploratory dietary patterns and incident type 2 diabetes: a federated meta-analysis of individual participant data from 25 cohort studies. Martínez-González MÁ, Soedamah-Muthu SS; EPIC-InterAct Consortium, Wareham NJ, Forouhi NG, Schulze MB. Eur J Nutr. 61(7):3649-3667. 2022 (PMID: 35641800)
  • GRANADA consensus on analytical approaches to assess associations with accelerometer-determined physical behaviours (physical activity, sedentary behaviour and sleep) in epidemiological studies. Migueles JH, Aadland E, Andersen LB, Brønd JC, Chastin SF, Hansen BH, Konstabel K, Kvalheim OM, McGregor DE, Rowlands AV, Sabia S, van Hees VT, Walmsley R, Ortega FB; External review group. Br J Sports Med. 56(7):376-384. 2022 (PMID: 33846158)
  • Association between depressive symptoms and pericardial fat in healthy older men and women. Miller NE, Steptoe A. Sci Rep. 12(1):13959. 2022 (PMID: 35978037)
  • Association of alcohol use with years lived without major chronic diseases: A multicohort study from the IPD-Work consortium and UK Biobank. Nyberg ST, Batty GD, Pentti J, Madsen IEH, Alfredsson L, Bjorner JB, Borritz M, Burr H, Ervasti J, Goldberg M, Jokela M, Knutsson A, Koskinen A, Lallukka T, Lindbohm JV, Nielsen ML, Oksanen T, Pejtersen JH, Pietiläinen O, Rahkonen O, Rugulies R, Shipley MJ, Sipilä PN, Sørensen JK, Stenholm S, Suominen S, Väänänen A, Vahtera J, Virtanen M, Westerlund H, Zins M, Singh-Manoux A, Kivimäki M. Lancet Reg Health Eur. 19:100417. 2022 (PMID: 35664051)
  • Inter- and intra-individual variation in brain structural-cognition relationships in aging. Patel R, Mackay CE, Jansen MG, Devenyi GA, O'Donoghue MC, Kivimäki M, Singh-Manoux A, Zsoldos E, Ebmeier KP, Chakravarty MM, Suri S. Neuroimage. 257:119254. 2022 (PMID: 35490915)
  • Contribution of smoking towards the association between socioeconomic position and dementia: 32-year follow-up of the Whitehall II prospective cohort study. Raggi M, Dugravot A, Valeri L, Machado-Fragua MD, Dumurgier J, Kivimaki M, Sabia S, Singh-Manoux A.  Lancet Reg Health Eur. 23:100516. 2022 (PMID: 36189426)
  • A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids. Ramdas S, Judd J, Graham SE, Kanoni S, Wang Y, Surakka I, Wenz B, Clarke SL, Chesi A, Wells A, Bhatti KF, Vedantam S, Winkler TW, Locke AE, Marouli E, Zajac GJM, Wu KH, Ntalla I, Hui Q, Klarin D et al.  Am J Hum Genet. 109(8):1366-1387. 2022 (PMID: 35931049) 
  • Neighborhood Socioeconomic Disadvantage and Childhood Body Mass Index Trajectories From Birth to 7 Years of Age. Rautava S, Turta O, Vahtera J, Pentti J, Kivimäki M, Pearce J, Kawachi I, Rautava P, Lagström H. Epidemiology. 33(1):121-130. 2022 (PMID: 34669629) 
  • Association of neighbourhood disadvantage and individual socioeconomic position with all-cause mortality: a longitudinal multicohort analysis. Ribeiro AI, Fraga S, Severo M, Kelly-Irving M, Delpierre C, Stringhini S, Kivimaki M, Joost S, Guessous I, Severi G, Giles G, Sacerdote C, Vineis P, Barros H; LIFEPATH Consortium. Lancet Public Health. 7(5):e447-e457. 2022 (PMID: 35487230)
  • How Selection Over Time Contributes to the Inconsistency of the Association Between Sex/Gender and Cognitive Decline Across Cognitive Aging Cohorts. Rouanet A, Avila-Rieger J, Dugravot A, Lespinasse J, Stuckwisch R, Merrick R, Anderson E, Long L, Helmer C, Jacqmin-Gadda H, Dufouil C, Judd S, Manly J, Sabia S, Gross A, Proust-Lima C. Am J Epidemiol.191(3):441-452. 2022 (PMID: 34521111)
  • Association of sleep duration at age 50, 60, and 70 years with risk of multimorbidity in the UK: 25-year follow-up of the Whitehall II cohort study.  Sabia S, Dugravot A, Léger D, Ben Hassen C, Kivimaki M, Singh-Manoux A. PLoS Med. 19(10):e1004109. 2022 (PMID: 36256607)
  • Importance of characterising sleep breaks within the 24-h movement behaviour framework. Sabia S, Yerramalla MS, Liu-Ambrose T. Int J Behav Nutr Phys Act. 19(1):3. 2022 (PMID: 34991607)
  • Association between kidney function and incidence of dementia: 10-year follow-up of the Whitehall II cohort study. Singh-Manoux A, Oumarou-Ibrahim A, Machado-Fragua MD, Dumurgier J, Brunner EJ, Kivimaki M, Fayosse A, Sabia S. Age Ageing. 51(1):afab259. 2022 (PMID: 35061870)
  • Risk of Macrovascular and Microvascular Disease in Diabetes Diagnosed Using Oral Glucose Tolerance Test With and Without Confirmation by Hemoglobin A1c: The Whitehall II Cohort Study. Tabák AG, Brunner EJ, Lindbohm JV, Singh-Manoux A, Shipley MJ, Sattar N, Kivimäki M. Circulation.146(13):995-1005. 2022 (PMID: 36004644)
  • Association of sleep with cognitive function during retirement transition: The Whitehall II Study. Teräs T, Rovio S, Pentti J, Head J, Kivimäki M, Stenholm S. Sleep. zsac237. 2022 (PMID: 36165428)
  • The long arm of childhood socioeconomic deprivation on mid- to later-life cognitive trajectories: A cross-cohort analysis. Tsang RSM, Gallacher JE, Bauermeister S. Alzheimers Dement (Amst). 14(1):e12322. 2022 (PMID: 35664888)
  • Aortic Pulse Wave Velocity as Adjunct Risk Marker for Assessing Cardiovascular Disease Risk: Prospective Study.  Valencia-Hernández CA, Lindbohm JV, Shipley MJ, Wilkinson IB, McEniery CM, Ahmadi-Abhari S, Singh-Manoux A, Kivimäki M, Brunner EJ. Hypertension. 79(4):836-843. 2022 (PMID: 35139665)
  • Organizational Justice and Long-term Metabolic Trajectories: A 25-Year Follow-up of the Whitehall II Cohort. Varga TV, Xu T, Kivimäki M, Mehta AJ, Rugulies R, Rod NH. J Clin Endocrinol Metab. 18;107(2):398-409. 2022 (PMID: 34596687)
  • Attribution of diabetes to the development of severe liver disease in the general population. Vuorinen M, Männistö VT, Salomaa V, Britton A, Jula A, Männistö S, Lundqvist A, Perola M, Åberg F. Liver Int. 42(10):2186-2194. 2022 (PMID: 35574998)
  • Objectively Measured Total Sedentary Time and Pattern of Sedentary Accumulation in Older Adults: Associations With Incident Cardiovascular Disease and All-Cause Mortality. Yerramalla MS, van Hees VT, Chen M, Fayosse A, Chastin SFM, Sabia S. J Gerontol A Biol Sci Med Sci. 77(4):842-850. 2022 (PMID: 35094083)
  • A saturated map of common genetic variants associated with human height. Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen AU, Jiang Y, Raghavan S, Miao J, Arias JD, Graham SE, Mukamel RE, Spracklen CN, Yin X, Chen SH, Ferreira T, Highland HH, Ji Y, Karaderi T et al.  Nature. 610(7933):704-712. 2022 (PMID: 36224396)