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Early Phase Cancer Trials Programme at UCL and UCLH

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Brain Trials

A LIST OF OUR EARLY PHASE brain cancer TRIALS WHICH ARE OPEN TO RECRUITMENT AT UNIVERSITY COLLEGE LONDON HOSPITALs

To find more information on UCLH Early Phase Cancer Clinical Trials, including eligibility criteria, click the hyperlinked Local Project Reference (LRP) ID, which will take you to the UCLH Find a Study database.

 

 

LOXO-RET-18036

A Phase 1/2 Study of the Oral RET Inhibitor LOXO-292 in Pediatric Patients with Advanced RET-Altered Solid or Primary Central Nervous System Tumours 

Local Project Reference:144862
Principal Investigator

Dr Sara Stoneham

Drug Class/ Treatment:

Selpercatinib (LOXO-292) (RET Inhibitor)

Patient Population:

Paediatric patients ≥ 6 months of age and ≤ 21 years of age at Cycle 1 Day 1 (C1D1)

  • RET fusion-positive solid tumor with measurable disease
  • RET-mutant MTC with measurable disease
  • RET fusion-positive primary CNS tumor with measurable disease.

Trial Hosted By - UCLH Cancer Clinical Trials Unit (CCTU)

 

Principal Investigator(s)