Publications

View our publications by year:

2024

• Blackstone J, Williams T, Nicholas JM, et al | Evaluating the effectiveness of simvastatin in slowing the progression of disability in secondary progressive multiple sclerosis (MS-STAT2): protocol for a multicentre, randomised controlled, double-blind, phase 3 clinical trial in the UK | BMJ Open 2024;14:e086414. doi: 10.1136/bmjopen-2024-086414

2023

• Monica Panca, James Blackstone, Oliver Stirrup, Maria-Teresa Cutino-Moguel, Emma Thomson, Christine Peters, Luke B. Snell, Gaia Nebbia, Alison Holmes, Anu Chawla, Nicholas Machin, Yusri Taha, Tabitha Mahungu, Tranprit Saluja, Thushan I. de Silva, Kordo Saeed, Cassie Pope, Gee Yen Shin, Rachel Williams, Alistair Darby, Darren L. Smith, Matthew Loose, Samuel C. Robson, Kenneth Laing, David G. Partridge, James R. Price, Judith Breuer | Evaluating the cost implications of integrating SARS-CoV-2 genome sequencing for infection prevention and control investigation of nosocomial transmission within hospitals | Journal of Hospital Infection 2023 | ISSN 0195-6701 | https://doi.org/10.1016/j.jhin.2023.06.005.

• Flowers, P., Leiser, R., Mapp, F., McLeod, J., Stirrup, O., Illingworth, C. J. R., Blackstone, J., & Breuer, J. (2023). A qualitative process evaluation using the behaviour change wheel approach: Did a whole genome sequence report form (SRF) used to reduce nosocomial SARS-CoV-2 within UK hospitals operate as anticipated? | British Journal of Health Psychology 00, 1– 25 | https://doi.org/10.1111/bjhp.12666

2022

• Muhammad Shipa, Liliana R Santos, Dao X Nguyen, Andrew Embleton-Thirsk, Mariea Parvaz, Lauren L Heptinstall, Ruth J Pepper, David A Isenberg, Caroline Gordon, Michael R Ehrenstein, Identification of biomarkers to stratify response to B-cell-targeted therapies in systemic lupus erythematosus: an exploratory analysis of a randomised controlled trial, The Lancet Rheumatology, 2022, ISSN 2665-9913, https://doi.org/10.1016/S2665-9913(22)00332-0
• Andrew J. Goldberg, Kashfia Chowdhury, Ekaterina Bordea, Iva Hauptmannova, James Blackstone, Deirdre Brooking, Elizabeth L. Deane, Stephen Bendall, Andrew Bing, Chris Blundell, Sunil Dhar, Andrew Molloy, Steve Milner, Mike Karski, Steve Hepple, Malik Siddique, David T. Loveday, Viren Mishra, Paul Cooke, Paul Halliwell, David Townshend, Simon S. Skene, and Caroline J. Doré, on behalf of the TARVA Study Group. Total Ankle Replacement Versus Arthrodesis for End-Stage Ankle Osteoarthritis: A Randomized Controlled Trial. Ann Intern Med. [Epub 15 November 2022]. doi:10.7326/M22-2058
• David M. Lowe, Li-An K. Brown, Kashfia Chowdhury, Stephanie Davey, Philip Yee, Felicia Ikeji, Amalia Ndoutoumou, Divya Shah, Alexander Lennon, Abhulya Rai, Akosua A. Agyeman, Anna Checkley, Nicola Longley, Hakim-Moulay Dehbi, Nick Freemantle, Judith Breuer, Joseph F. Standing, FLARE Investigators (2022) | Favipiravir, lopinavir-ritonavir, or combination therapy (FLARE): A randomised, double-blind, 2 × 2 factorial placebo-controlled trial of early antiviral therapy in COVID-19. PLOS Medicine 19(10): e1004120. doi.org/10.1371/journal.pmed.1004120
• Hayley Colton, Matthew D. Parker, Oliver Stirrup, James Blackstone, Matthew Loose, C. Patrick McClure, Sunando Roy, Charlotte Williams, Julie McLeod, Darren Smith, Yusri Taha, Peijun Zhang, Sharon Nienyun Hsu, Beatrix Kele, Kathryn Harris, Fiona Mapp, Rachel Williams, Paul Flowers, Judith Breuer, David G. Partridge, Thushan I. de Silva | Factors affecting turnaround time of SARS-CoV-2 sequencing for inpatient infection prevention and control decision making: Analysis of data from the COG-UK HOCI study | Journal of Hospital Infection, 2022, ISSN 0195-6701, https://doi.org/10.1016/j.jhin.2022.09.022.
• Oliver Stirrup, James Blackstone, Fiona Mapp, Alyson MacNeil, Monica Panca, Alison Holmes, Nicholas Machin, Gee Yen Shin, Tabitha Mahungu, Kordo Saeed, Tranprit Saluja, Yusri Taha, Nikunj Mahida, Cassie Pope, Anu Chawla, Maria-Teresa Cutino-Moguel, Asif Tamuri, Rachel Williams, Alistair Darby, David L Robertson, Flavia Flaviani, Eleni Nastouli, Samuel Robson, Darren Smith, Kenneth Laing, Irene Monahan, Beatrix Kele, Sam Haldenby, Ryan George, Matthew Bashton, Adam A Witney, Matthew Byott, Francesc Coll, Michael Chapman, Sharon J Peacock, COG‐UK HOCI Investigators, The COVID‐19 Genomics UK (COG‐UK) Consortium, Joseph Hughes, Gaia Nebbia, David G Partridge, Matthew Parker, James Richard Price, Christine Peters, Sunando Roy, Luke B Snell, Thushan I de Silva, Emma Thomson, Paul Flowers, Andrew Copas, Judith Breuer | (2022) Effectiveness of rapid SARS-CoV-2 genome sequencing in supporting infection control for hospital-onset COVID-19 infection: multicenter, prospective study | eLife 11:e78427.
• Thomas Williams, Sarah Alexander, James Blackstone, Floriana De Angelis, Nevin John, Anisha Doshi, Judy Beveridge, Marie Braisher, Emma Gray & Jeremy Chataway on behalf of the MS-SMART and MS-STAT2 Investigators | Optimising recruitment in clinical trials for progressive multiple sclerosis: observational analysis from the MS-SMART and MS-STAT2 randomised controlled trials | Trials 23, 644 (2022). https://doi.org/10.1186/s13063-022-06588-z
• Annegret Hella Dahlmann-Noor, John A Greenwood, Andrew Skilton, Daniel Baker, Siobhan Ludden, Amanda Davis, Hakim-Moulay Dehbi, Steven C Dakin. Phase 2a randomised controlled feasibility trial of a new ‘balanced binocular viewing’ treatment for unilateral amblyopia in children age 3–8 years: trial protocol. BMJ Open 2022;12:e051423. doi: 10.1136/bmjopen-2021-051423
• Nithya Prasannan, Melissa Heightman, Toby Hillman, Emma Wall, Robert Bell, Anna Kessler, Lucy Neave, Andrew James Doyle, Akshitha Devaraj, Deepak Singh, Hakim-Moulay Dehbi, Marie Scully; Impaired exercise capacity in post-COVID syndrome: the role of VWF-ADAMTS13 axis. Blood Adv 2022; bloodadvances.2021006944. doi: https://doi.org/10.1182/bloodadvances.2021006944
• Hakim-Moulay Dehbi, Andrew Embleton-Thirsk, Zachary Ryan McCaw | Sample size calculation for randomized selection trials with a time-to-event endpoint and a margin of practical equivalence | Statistics in Medicine. 2022; 1- 12. doi:10.1002/sim.9490
• Muhammad Ruhul Amin Shipa, Su-Ann Yeoh, Andrew Embleton-Thirsk, Dev Mukerjee, Michael R Ehrenstein | The synergistic efficacy of hydroxychloroquine with methotrexate is accompanied by increased erythrocyte mean corpuscular volume | Rheumatology, Volume 61, Issue 2, February 2022, Pages 787–793, https://doi.org/10.1093/rheumatology/keab403
• James Blackstone, Oliver Stirrup, Fiona Mapp, Monica Panca, Andrew Copas, Paul Flowers, Leanne Hockey, James Price, David Partridge, Christine Peters, Thushan de Silva, Gaia Nebbia, Luke B Snell, Rachel McComish, The COVID-19 Genomics UK (COG-UK) Consortium, Judith Breuer | Protocol for the COG-UK hospital-onset COVID-19 infection (HOCI) multicentre interventional clinical study: evaluating the efficacy of rapid genome sequencing of SARS-CoV-2 in limiting the spread of COVID-19 in UK NHS hospitals | doi: 10.1136/bmjopen-2021-052514
• Jonathan G Best, Liz Arram, Norin Ahmed, Maryam Balogun, Kate Bennett,  Ekaterina Bordea, Marta G Campos, Emilia Caverly,  Marisa Chau, Hannah Cohen, Hakim-Moulay Dehbi,  Caroline J Doré, Stefan T Engelter, Robert Fenner, Nick Freemantle, Rachael Hunter, Martin James, Gregory YH Lip, Macey L Murray, Bo Norrving, Nikola Sprigg, Roland Veltkamp, Iwona Zaczyk, David J Werring, the OPTIMAS investigators | Optimal timing of anticoagulation after acute ischemic stroke with atrial fibrillation (OPTIMAS): Protocol for a randomized controlled trial | doi.org/10.1177/17474930211057722

2021

• Li-An K. Brown, Nick Freemantle, Judy Breuer, Hakim-Moulay Dehbi, Kashfia Chowdhury, Gemma Jones, Felicia Ikeji, Amalia Ndoutoumou, Krishneya Santhirakumar, Nicky Longley, Anna M. Checkley, Joseph F. Standing & David M. Lowe | Early antiviral treatment in outpatients with COVID-19 (FLARE): a structured summary of a study protocol for a randomised controlled trial. Trials 22, 193 (2021). doi.org/10.1186/s13063-021-05139-2
• Asma Sarwar, Jennifer Van Griethuysen, Jasmine Waterhouse, Hakim-Moulay Dehbi, Gemma Eminowicz and Mary McCormack. Stratified follow-up for endometrial cancer: a move to more personalized cancer care. International Journal of Gynecologic Cancer 2021;31:1564-1571.
• Melissa Heightman, Jai Prashar, Toby E Hillman, Michael Marks, Rebecca Livingston, Heidi A Ridsdale, Kay Roy, Robert Bell, Michael Zandi, Patricia McNamara, Alisha Chauhan, Emma Denneny, Ronan Astin, Helen Purcell, Emily Attree, Lyth Hishmeh, Gordon Prescott, Rebecca Evans, Puja Mehta, Ewen Brennan, Jeremy S Brown, Joanna Porter, Sarah Logan, Emma Wall, Hakim-Moulay Dehbi, Stephen Cone, Amitava Banerjee. Post-COVID-19 assessment in a specialist clinical service: a 12-month, single-centre, prospective study in 1325 individuals. BMJ Open Respiratory Research 2021;8:e001041. doi: 10.1136/bmjresp-2021-001041
• Hakim-Moulay Dehbi, John O’Quigley, Alexia Iasonos. Controlled backfill in oncology dose-finding trials. Contemporary Clinical Trials, Volume 111, December 2021, 106605 https://doi.org/10.1016/j.cct.2021.106605
• Marjan Jahangiri, Rajdeep Bilkhu, Andrew Embleton-Thirsk, Hakim-Moulay Dehbi, Krishna Mani, Jon Anderson, Vassilios Avlonitis, Max Baghai, Inderpaul Birdi, Karen Booth, Amal Bose, Norman Briffa, Keith Buchan, Sunil Bhudia, Alex Cale, Indu Deglurkar, Shakil Farid, Leonidas Hadjinikolaou, Martin Jarvis, Seyed Hossein Javadpour, Reubendra Jeganathan, Manoj Kuduvalli, Kulvinder Lall, Jorge Mascaro, Dheeraj Mehta, Sunil Ohri, Prakash Punjabi, Rajamiyer Venkateswaran, Paul Ridley, Christopher Satur, Serban Stoica, Uday Trivedi, Afzal Zaidi, Patrick Yiu, Narain Moorjani, Simon Kendall, Nick Freemantle. Surgical aortic valve replacement in the era of transcatheter aortic valve implantation: a review of the UK national database. BMJ Open 2021;11:e046491. doi: 10.1136/bmjopen-2020-046491
• Hayes, Aimee R. MBBS∗; Furnace, Myles BMBS∗; Shah, Ruchir MBBS†; Rundell, Caroline MBBS†; Muller, Gregory MBBS†; Dehbi, Hakim-Moulay PhD‡; Luong, Tu Vinh MD∗,§; Toumpanakis, Christos PhD∗; Caplin, Martyn E. DM∗; Krell, Daniel DPhil∗; Thirlwell, Christina PhD∥; Mandair, Dalvinder MD∗ High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms and Improved Prognostic Stratification With the New World Health Organization 2019 Classification, Pancreas: April 2021 - Volume 50 - Issue 4 - p 516-523, doi: 10.1097/MPA.0000000000001808 
• Li-An K. Brown, Nick Freemantle, Judy Breuer, Hakim-Moulay Dehbi, Kashfia Chowdhury, Gemma Jones, Felicia Ikeji, Amalia Ndoutoumou, Krishneya Santhirakumar, Nicky Longley, Anna M. Checkley, Joseph F. Standing & David M. Lowe Early antiviral treatment in outpatients with COVID-19 (FLARE): a structured summary of a study protocol for a randomised controlled trial. Trials 22, 193 (2021). https://doi.org/10.1186/s13063-021-05139-2
• Louise China, Ph.D., Nick Freemantle, Ph.D., Ewan Forrest, M.D., Yiannis Kallis, Ph.D., Stephen D. Ryder, D.M., Gavin Wright, Ph.D., Andrew J. Portal, M.D., Natalia Becares Salles, Ph.D., Derek W. Gilroy, Ph.D., and Alastair O’Brien, Ph.D. for the ATTIRE Trial Investigators | A Randomized Trial of Albumin Infusions in Hospitalized Patients with Cirrhosis | DOI: 10.1056/NEJMoa2022166
• Jahangiri M, Bilkhu R, Embleton-Thirsk A, et al | Surgical aortic valve replacement in the era of transcatheter aortic valve implantation: a review of the UK national database | BMJ Open 2021;11:e046491. doi: 10.1136/bmjopen-2020-046491
• Muhammad Shipa, MBBS; Andrew Embleton-Thirsk, PhD; Mariea Parvaz, MSc; Liliana Ribeiro Santos, MD; Patrick Muller, MSc; Kashfia Chowdhury, MSc; David A. Isenberg, MD; Caroline J. Doré, BSc; Caroline Gordon, MA, MD; Michael R. Ehrenstein, MBBS, PhD; BEAT-LUPUS Investigators* | Effectiveness of Belimumab After Rituximab in Systemic Lupus Erythematosus | https://doi.org/10.7326/M21-2078
• Sarveen Gajebasia, Toby Jennison, James Blackstone, Razi Zaidi, Patrick Muller, Andrew Goldberg | Patient Reported Outcome Measures in Ankle Replacement Versus Ankle Arthrodesis – A Systematic Review | The Foot, available online 29 October 2021, 101874, https://doi.org/10.1016/j.foot.2021.101874
• Daniel FP Larkin, Kashfia Chowdhury, Caroline J Doré, Catey Bunce, Jennifer M Burr, Emilia Caverly, Lisa French, Dimitra Kopsini, Anne Klepacz, Mathew Raynor, Matthew Edwards & Stephen J Tuft | Epithelium-off corneal cross-linking surgery compared with standard care in 10- to 16-year-olds with progressive keratoconus: the KERALINK RCT | Efficacy and Mechanism Evaluation Volume: 8, Issue: 15, Published in October 2021, https://doi.org/10.3310/eme08150
• Oliver Stirrup, Florencia Boshier, Cristina Venturini, José Afonso Guerra-Assunção, Adela Alcolea-Medina, Angela Beckett, Themoula Charalampous, Ana da Silva Filipe, Sharon Glaysher, Tabassum Khan, Raghavendran Kulasegaran Shylini, Beatrix Kele, Irene Monahan, Guy Mollett, Matthew Parker, Emanuela Pelosi, Paul Randell, Sunando Roy, Joshua Taylor, Sophie Weller, Eleri Wilson-Davies, Phillip Wade, Rachel Williams, The COG-UK-HOCI Variant substudy consortium, The COVID-19 Genomics UK (COG-UK) consortium, Andrew Copas, Maria-Teresa Cutino-Moguel, Nick Freemantle, Andrew C Hayward, Alison Holmes, Joseph Hughes, Tabitha Mahungu, Gaia Nebbia, David Partridge, Cassie Pope, James Price, Samuel Robson, Kordo Saeed, Thushan de Silva, Luke Snell, Emma Thomson, Adam A Witney and Judith Breuer | SARS-CoV-2 lineage B.1.1.7 is associated with greater disease severity among hospitalised women but not men: multicentre cohort study | BMJ Open Respiratory Research 2021;8:e001029.
• Day AC, Burr JM, Bennett K, Hunter R, Bunce C, Doré CJ, Nanavaty MA, Balaggan KS, Wilkins MR. Femtosecond laser-assisted cataract surgery compared with phacoemulsification: the FACT non-inferiority RCT. Health Technol Assess 2021;25(6).
• Bennett S, Cross H, Coughtrey A, Heyman I, Ford T, Chorpita B, Moss-Morris R, Byford S, Dalrymple E, Reilly C, Stephenson T, Doré CJ, Varadkar S, Blackstone J, Chowdhury K, Ganguli P, Deane L, Shafran R. M.I.C.E – Mental Health Intervention for Children with Epilepsy: A randomised controlled, multi-centre clinical trial evaluating the clinical and cost-effectiveness of MATCH-ADTC in addition to usual care compared to usual care alone for children and young people with common mental health disorders and epilepsy– Study protocol. Trials 2021;22,132.
• Alba X. Realpe, James Blackstone, Damian R. Griffin, Andrew J. F. Bing, Michael Karski, Stephen A. Milner, Malik Siddique, Andrew Goldberg | Barriers to recruitment to an orthopaedic randomized controlled trial comparing two surgical procedures for ankle arthritis, a qualitative study | Bone Jt Open 2021;2(8):631–637
• Oliver Stirrup, Joseph Hughes, Matthew Parker, David G Partridge, James G Shepherd, James Blackstone, Francesc Coll, Alexander Keeley, Benjamin B Lindsey, Aleksandra Marek, Christine Peters, Joshua B Singer, The COVID-19 Genomics UK (COG-UK) consortium, Asif Tamuri, Thushan I de Silva, Emma C Thomson, Judith Breuer | Rapid feedback on hospital onset SARS-CoV-2 infections combining epidemiological and sequencing data | eLife 2021;10:e65828 DOI: 10.7554/eLife.65828
• Nirosen Vijiaratnam, Christine Girges, Grace Auld, Marisa Chau, Kate Maclagan, Alexa King, Simon Skene, Kashfia Chowdhury, Steve Hibbert, Huw Morris, Patricia Limousin, Dilan Athauda, Camille B Carroll, Michele T Hu, Monty Silverdale, Gordon W Duncan, Ray Chaudhuri, Christine Lo, Silvia Del Din, Alison J Yarnall, Lynn Rochester, Rachel Gibson, John Dickson, Rachael Hunter, Vincenzo Libri, Thomas Foltynie | Exenatide once weekly over 2 years as a potential disease-modifying treatment for Parkinson’s disease: protocol for a
• multicentre, randomised, double blind, parallel group, placebo controlled, phase 3 trial: The ‘Exenatide-PD3’ study | BMJ Open Neurology, Volume 11, Issue 5, 12 May 2021
• Daniel F P Larkin, Kashfia Chowdhury, Jennifer M Burr, Mathew Raynor, Matthew Edwards, Stephen J Tuft, Catey Bunce, Emilia Caverly, Caroline Doré | EFFECT OF CORNEAL CROSS-LINKING vs STANDARD CARE ON KERATOCONUS PROGRESSION IN YOUNG PATIENTS: THE KERALINK RANDOMIZED CONTROLLED TRIAL | PMID: 33892046 | DOI: 10.1016/j.ophtha.2021.04.019

2020

• Dehbi, HM., Hackshaw, A. Sample size calculation in randomised phase II selection trials using a margin of practical equivalence. Trials 21, 301 (2020). https://doi.org/10.1186/s13063-020-04248-8
• Muller P, Skene SS, Chowdhury K, Cro S, Goldberg AJ, Doré CJ, on behalf of the TARVA Study Group. A randomised, multi-centre trial of total ankle replacement versus ankle arthrodesis in the treatment of patients with end stage ankle osteoarthritis (TARVA): statistical analysis plan. Trials 2020;21, 197.
• Larkin F, Chowdhury K, Burr JE, Bunce C, Doré CJ. The KERALINK trial of corneal cross-linking for progressive keratoconus in children. Methodology and baseline patient characteristics. Annual meeting of the Association-for Research-in-Vision-and-Ophthalmology (ARVO) Investigative Ophthalmology and Visual Science 1 June 2020;61(7)
• Chowdhury K, Doré CJ, Bunce C, Larkin DFP. Corneal cross-linking versus standard care in children with keratoconus – a randomised, multicentre, observer-masked trial if efficacy and safety (KERALINK): a statistical analysis plan. Trials 2020;21:523.
• Gilson R, Nugent D, Bennett K, Doré CJ, Murray ML, Meadows J, Haddow L J, Lacey C, Sandmann F, Jit M, Soldan K, Tetlow M, Caverly E, Nathan M, Copas A J. Imiquimod versus podophyllotoxin, with and without human papillomavirus vaccine, for anogenital warts: the HIPvac factorial RCT. Health Technology Assessment 2020;24(47)
• Day AC, Burr JM, Bennett K, Doré CJ, Bunce C, Hunter R, Nanavaty MA, Balaggan KS, Wilkins MR, on behalf of the FACT trial group. Femtosecond laser-assisted cataract surgery compared with phacoemulsification surgery (FACT). A randomised non-inferiority trial, 1 year outcomes. Journal of Cataract and Refractive Surgery 2020
• Day AC, Burr JM, Bennett K, Hunter R, Bunce C, Doré CJ, Nanavaty MA, Balaggan KS, Wilkins MR. Femtosecond laser-assisted cataract surgery compared with phacoemulsification: the FACT non-inferiority RCT. Health Technol Assess 2021;25(6).
• Muller P, Chowdhury K, Gordon C, Ehrenstein MR, Doré CJ. Safety and efficacy of belimumab after B cell depletion therapy in systemic LUPUS erythematosus (BEAT-LUPUS) trial: statistical analysis plan. Trials 2020;21, 652.
• Ruth Brauer, Li Wei, Tiantian Ma, Dilan Athauda, Christine Girges, Nirosen Vijiaratnam, Grace Auld, Cate Whittlesea, Ian Wong, Tom Foltynie | Diabetes medications and risk of Parkinson’s disease: a cohort study of patients with diabetes | Brain, Volume 143, Issue 10, October 2020, Pages 3067–3076
• Hakim‐Moulay Dehbi  David M. Lowe  John O'Quigley. Early phase dose‐finding trials in virology
• Alexander C.Day PhD; Jennifer M.Burr MD; Kate Bennett MSc; Catey Bunce DSc; Caroline J.Doré BSc; Gary S.Rubin PhD; Mayank A.Nanavaty PhD; Kamaljit S.Balaggan PhD; Mark R.Wilkins MD. Femtosecond Laser-Assisted Cataract Surgery Versus Phacoemulsification Cataract Surgery (FACT): A Randomized Noninferiority Trial.

2019

• Bennett S, Heyman I, Coughtrey A, Buszewicz M, Byford S, Doré CJ, Fonagy P, Ford T, Moss Morris R, Stephenson T, Varadkar S, Walker E, Shafran R. Assessing feasibility of routine identification tools for mental health disorder in neurology clinics. Archives of Disease in Childhood 2019;104:1161–1166.
• Chowdhury K, Doré CJ, Burr JM, Bunce C, Raynor M, Edwards M, Larkin DFP. A randomised, controlled, observer-masked trial of corneal cross-linking for progressive keratoconus in children: the KERALINK protocol. BMJ Open 2019;9:e028761.
• Gilson R, Bennett K, Sandmann F, Murray M, Doré CJ, Haddow L, Nugent D, Lacey C, Jit M, Soldan K, Caverly E, Nathan M, Copas A. Efficacy and cost-effectiveness of qHPV vaccine with imiquimod or podophyllotoxin for patients with anogenital warts (HIPvac). (Abstract) Sexually Transmitted Diseases 2019;95(Suppl 1), A50-A51.
• Alexis Jones, Patrick Muller, Caroline J Dore, Felicia Ikeji, Emilia Caverly, Kashfia Chowdhury, David A Isenberg, Caroline Gordon, Michael R Ehrenstein (2019). Belimumab after B cell depletion therapy in patients with systemic lupus erythematosus (BEAT Lupus) protocol: a prospective multicentre, double-blind, randomised, placebo-controlled, 52-week phase II clinical trial. BMJ.
• Lewis C, Hutchinson J C, Riddington M, Hill M, Arthurs O J, Fisher J, Wade A, Doré C J, Chitty L S & Sebire N J. Minimally invasive autopsy for fetuses and children based on a combination of post-mortem MRI and endoscopic examination: a feasibility study. https://doi.org/10.3310/hta23460
• Adrian J. Hobbs, Amie J. Moyes, Reshma S. Baliga, Dipa Ghedia, Rachel Ochiel, Yvonne Sylvestre, Caroline J. Doré, Kashfia Chowdhury, Kate Maclagan, Harriet L. Quartly, Reecha Sofat, Angelique Smit, Benjamin E. Schreiber, J. Gerry Coghlan, Raymond J. MacAllister. Neprilysin inhibition for pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled, proof-of-concept trial. https://doi.org/10.1111/bph.14621

 

All rights reserved.