Brain Sciences


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Eye test may detect Parkinson’s before symptoms appear
Eye examination

A new low-cost and non-invasive eye test could detect Parkinson’s disease before symptoms including tremors and muscle stiffness develop, according to new research led by scientists at UCL. 

Researchers at the UCL Institute of Ophthalmology have discovered a new method of observing changes in the retina which can be seen in Parkinson’s before changes in the brain occur and the first symptoms become evident.

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Alcohol abuse drug can be repurposed to treat a blinding disorder
Ball-and-stick model of the disulfiram molecule

New research from University College London, Moorfields Eye Hospital and Duke University School of Medicine has identified a gene that drives scarring, together with a rapidly translatable therapy, for the UK’s most common cause of blinding conjunctivitis. The results demonstrate that the drug disulfiram, licensed for the control of alcohol abuse, normalises human and mouse scar-making cell (fibroblast) functions and inhibits mouse ocular mucosal (conjunctival) scarring. Fight for Sight, UCL Business, and Moorfields Eye Charity funded the study, which is published in the Journal of Clinical Investigation Insight on 4 August 2016.

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