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Professor Ivan Gout
Course Leader
Dept. of Structural & Molecular Biology
The main focus of my research is the study of basic mechanisms by which cell growth and metabolism are regulated in normal and cancer cells. There are two major areas of interest in my laboratory a) regulation of cell growth, metabolism and proliferation via the mTOR/S6K pathway and b) the role of Coenzyme A and its derivatives in cellular metabolism and gene expression. The development of novel diagnostic and therapeutic approaches for cancer is the ultimate goal of both programmes, which we pursue through collaboration with academic and industrial partners.
Recent publications:
Coenzyme A, protein CoAlation and redox regulation in mammalian cells
Protein CoAlation and antioxidant function of Coenzyme A in prokaryotic cells
Professor Geraint Thomas
Dept of Cell & Developmental Biology
Scientific interests: cell signalling mechanisms, including protein kinases, phospholipid kinases, phospholipases and GTP-binding proteins. Raman microspectrosopic imaging in cancer diagnostics. General biochemistry and molecular cell biology.
Professor Julie Daniels
Director Cells for Sight, Stem Cell Research Unit
Dept of Ocular Biology & Therapeutics
UCL Institute of Ophthalmology
Professor Daniels is a leader in translational research into the use of stem cells for repair of the human ocular surface. Understanding the biological mechanisms that cause pathologies of ageing, and how such pathologies lead to mortality. Insulin/IGF-1 signalling and dietary restriction and biology of ageing.
Professor David Gems
Deputy Director Institute of Healthy Ageing
Scientific interests: underestanding the genes and biochemical processes by which reduced insulin/IGF-1 signalling and dietary restriction increase lifespan. Using C.elegans as an ideal model organism to study ageing, the lab hopes to unravel the mystery of human ageing.
Blue Death: the frontiers of ageing research - a Wellcome Trust film
