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Dr Lorenzo Fabrizi

Dr Lorenzo Fabrizi

Principal Research Fellow

Neuro, Physiology & Pharmacology

Div of Biosciences

Joined UCL
7th Jan 2008

Research summary

The rate of premature births is  rising in many European countries. In the UK the number of babies born at 22-25 weeks gestation and admitted to intensive care increased by 44% between 1995 and 2006 with a survival rate improvement of 13%. However, little is known about how the brain sensory functions mature in early development and the influence that premature sensory experiences have on their normal trajectory. With my research, I aim at understanding the development of cortical functions and underlying networks using non-invasive brain monitoring techniques such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI). This is a collaborative project involving academics and clinicians from UCL and King's College London and their partner hospitals UCLH and St Thomas'.

Teaching summary

I am deputy organiser (with Prof Pedarzani) for the undergraduate modules NEUR0010/11/12 on “Neurobiology of Brain Injury and Disease”, delivered to 3rd and 4th year Neuroscience undergraduates.

I teach a variety of subjects to 1st, 2nd and 3rd year undergraduate students within and outside my field of research expertise. I teach the neurophysiology of vision for PHOL0004, the basis for brain imaging for NEUR0020, the role of brain imaging of pain for ANT0013 and a general introduction to brain imaging for NEUR0005. I also run revision and science skills tutorials for NEUR0005 and NEUR0010/11/12. I set and mark exam questions for these modules and mark posters and presentations of student library and lab projects.

I previously taught early sensory networks and activity dependence on the MSc Neuroscience and introduction to biomechanics and physiological measurement for the Medical Physics BSc course.

Education

University College London
Doctorate, Doctor of Philosophy | 2008
Politecnico di Milano
First Degree, Laurea | 2003

Biography

I graduated in Biomedical Engineering at the Politecnico di Milano University (Italy) and in 2008 completed my PhD in Medical Physics and Bioengineering at UCL investigating the use of Electrical Impedance Tomography in epilepsy diagnosis.  I then moved to the department of Neuroscience, Physiology and Pharmacology to explore the development of pain perception in human premature neonates in collaboration with the neonatal ward at UCLH using Electroencephalography (EEG). I am now a group leader funded by the Medical Research Council UK working at UCL and King’s College London in collaboration with their main university hospitals to study the development of spontaneous neuronal activity and of the somatosensory system in premature neonates integrating EEG and functional Magnetic Resonance Imaging information. My work is rooted in neonatology, neuroimaging, biomedical signal processing and neuroscience attracting collaboration from these disciplines, including the internationally renowned Centre for the Developing Brain. The results of my research have been published in leading scientific journals, such as Current Biology, eLife and The Lancet and featured in national and international newspapers and magazines, including New Scientist, the Washington Post and The Indipendent. I have organised workshops and presented my work at meetings across Europe and in the United States, and my research received various recognitions including the UCL Neuroscience Early Career Prize and a Merit Award from the Organization for Human Brain Mapping. I am also part of the Neuroscience Career Network Committee at UCL and regularly review articles for various general science and specialised journals.

Publications