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Patel lab papers cover discovery of elusive receptor proteins for Ca2+ mobilizing messenger NAADP

25 November 2021

The recent discovery of elusive receptor proteins for the Ca2+ mobilizing messenger NAADP were recently discussed by Professor Sandip Patel and colleagues in a commentary in Cell Calcium and a review in Trends in Biochemical Sciences.

image of receptor proteins for the Ca2+ mobilizing messenger NAADP

Papers from Professor Sandip Patel (UCL CDB) and colleagues, published in Cell Calcium and Trends in Biochemical Sciences discuss recent work to identifying the elusive NAADP-BPs as Jupiter microtubule associated homolog 2 (JPT2) and ‘like-Sm’ protein 12 (LSM12). These discoveries enable new insight into this signaling pathway and the role of NAADP in cellular physiology and disease.