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NPP Seminar - Distinguished Professor David Kleinfeld, UCSD
22 February 2023, 1:00 pm–2:00 pm
Title: Coupled arteriole oscillations in the brain and what they tell about neuronal activity
Event Information
Open to
- UCL staff | UCL students | UCL alumni
Availability
- Yes
Organiser
-
Charlette Bent-Gayle
Location
-
131 A V HillMedical Sciences and AnatomyGower StreetlondonWC1E 6BTUnited Kingdom
Academic Host: Angus Silver
Abstract: Pial arterioles form an interconnected network that distribute blood across the cortical mantle and source nourishment to brain cells. Far from a passive network, the diameter of these arterioles intrinsically oscillate in the ~ 0.1 Hz vasomotor band. The pial arterioles integrate activity from neighboring arterioles, underlying neurons, and subcortical nuclei to produce space-time patterns of coherent oscillations. I will discuss optical and MR experiments and their analysis that seek to understand these patterns and exploit them to infer neuronal activity
About the Speaker
Distinguished Professor David Kleinfeld
at UCSanDiego
David Kleinfeld received his Ph.D. from UCSD and was a Member of Technical Staff at the former AT&T Bell Laboratories prior to joining the faculty at UCSD. He is a recipient of a David and Lucile Packard Foundation Interdisciplinary Science Award, a NIH Directors Pioneer Award, a NINDS Research Program Award, and currently holds the Experimental Biophysics Endowed Chair through Physics. David is a fellow of the American Association for the Advancement of Science and a member of the American Academy of Arts and Sciences. He currently leads the Specialization on Computational Neuroscience through the Neurosciences Graduate Program.
More about Distinguished Professor David Kleinfeld