Biography
Since joining CoMPLEX in Oct 2013, I have been involved in a number of exciting interdisciplinary projects. These include the development of fast, computational algorithms for superresolution Imaging at the Laboratory for Molecular Cell Biology (LMCB), supervised by Dr Ricardo Henriques and Dr Alan Lowe. Research into the maintenance of cytoplasmic domains and nuclear independence in polynucleated cell structures using fluorescence recovery after photobleaching in budding yeast and modelling of nucleocytoplasmic protein shuttling in fused cells, also at LMCB, supervised by Prof Buzz Baum and Dr Christopher Stefan. An experimental investigation of the photophysics of Oregon Green 488 and its suitability to biological research applications by fluorescence lifetime imaging, time correlated single photon counting and stimulated emission depletion, supervised by Dr Angus Bain in the Biological Physics group, in the Physics and Astronomy department at UCL.
For my CoMPLEX summer research project I contributed to characterising and modelling the dynamics of microtubule growth and further developing ground truth simulations of microscopy data of in vitro microtubules for use in determining the accuracy of microtubule end tracking algorithms. For this project I was based in the Microtubule Cytoskeleton Laboratory at Cancer Research UK and the Image Analysis group in the UCL Computer Science Department, supervised by Dr Thomas Surrey and Dr Lewis Griffin.
I completed my Master of Research degree in Modelling Biological Complexity at the end of September 2014 receiving a distinction and am now studying for a PhD at the (LMCB), supervised by Dr Ricardo Henriques and Dr Alan Lowe.
Prior to joining CoMPLEX, I graduated from The University of Birmingham (UoB), in July 2012, with a 1st class MSci degree in Physics. In the summers of 2006 and 2007 I worked in the Biomedical Optics Research Laboratory (BORL) at UCL, supervised by Prof Elwell, where I developed electronics and optics for use in Near Infrared Spectroscopy devices used to image the haemodynamics of the neonatal brain. During my undergraduate I was involved in research projects involving Image Processing, Plasmonics, Faraday Rotation and the Photoluminescence of Nanocrystals. In the summer of 2011 I worked at the Nanoscale Physics Reseach Laboratory (NPRL) at UoB, supervised by Prof Palmer, where I developed hardware and software solutions for use in High Resolution Electron Energy Loss Spectroscopy. In 2012, my MSci physics project at UoB, supervised by Dr Neil Thomas on coupled chemically driven ratchets as model for the behaviour of F0F1 ATP Synthase won the Tessella Prize for the "Most Innovative Use of Software in a Final Year Project". From Sep 2012 to Apr 2013 I worked in the ATP Synthase group at the Mitochondrial Biology Unit (MBU), supervised by Prof John Walker, where I worked on elucidating the structure of intermediate states in the catalytic cycle of F0F1 ATP Synthase by x-ray crystallography. From July 2013 to Sep 2013 I worked in the Microtubule Cytoskeleton Laboratory at Cancer Research UK, supervised by Dr Thomas Surrey, where I developed ground truth simulations of microscopy data for use in determining the resolution limit of microtubule end structures.
Curriculum Vitae
A detailed Curriculum Vitae can be downloaded here.