World TB Day 2018

On 24 March, the world commemorates the day in 1882 when Dr Robert Koch announced his discovery of Mycobacterium tuberculosis. We take this opportunity each year to highlight contemporary research innovation and future challenges in a one-day symposium co-organised by LSHTM and UCL.

For the 2018 event, our audience - in person at the John Snow Lecture Theatre and the hundreds who watched online - heard about a wide variety of studies as well as an impassioned call to action from Nick Herbert MP, who is a key player in preparations for September's UN high-level meeting on TB.  Another treat was the launch of Public Health England's LTBI public awareness film.

We were also delighted to link up with our friends at UCSF for our very first "super-symposium".  UCSF streamed our final session in their auditorium before we handed over to them and streamed their talks from while our delegates enjoyed a post-symposium drink.  For more about the UCSF event, visit their website.

We are still accepting your papers for a special collection that we've been putting together with F1000 Research, so please don't hesitate to send those in.  And if you have any feedback on the 2018 symposium and thoughts for 2019's event, please contact us at tb@ucl.ac.uk.

Recordings of the talks are now available here:

Full programme

9.00-9.35amRegistration and coffee
9.35-9.50amWelcome address
Prof David Moore (LSHTM) and Prof Michael Arthur (UCL)
9.50-10.00amGlobal TB Advocacy in 2018
Nick Herbert MP (APPG on Global TB, and Global TB Caucus)
10.00-11.00amSession 1: Drug resistant TB - what is it, where is it and how is it spread?
Prof Tim McHugh (UCL, chair)
Prof Francois Balloux (UCL)
Global transmission of drug resistant Mycobacterium tuberculosis L4 strains
Dr Marc Lipman (UCL)
Non-tuberculous mycobacteria (NTM) and antibiotic resistance
Dr Helen Stagg (UCL)
Isoniazid monoresistant tuberculosis: Bad Medicine?
Prof Alison Grant (LSHTM)
Transmission of drug-resistant TB
11.00-11.30amCoffee and networking break 
11.30am-12.30pm Session 2: What should we do about drug-resistant TB?
Prof Katherine Fielding (LSHTM, chair)
Dr Ilaria Motta (MSF)
TB-Practecal trial updates
Dr Karina Kielmann (Queen Margaret University)
Putting systems in place to address drug-resistant TB: the role of 'hardware' and 'software'
Dr Frank Kloprogge (UCL)
Pharmacodynamic drug-drug interactions in antibiotic treatment combinations
Prof Andrew Nunn (UCL)
STREAM preliminary results: what do they tell us?
12.30-1.30pmLunch break 
1.30-1.45pmPublic Health England: raising public awareness of LTBI
Dr Dominik Zenner (PHE), Dr Matthew Burman (QMUL), Lee Ellis, Mark Nunn (In Tune for Life)
1.45-3.00pm Session 3: Debate - Do we need host-directed therapies if we have a universal drug regimen?
Dr Helen Fletcher (LSHTM, chair)
Dr Daniel Kalman (University of Emory Medical School)
Dr Derek Sloan (University of St Andrews)
3.00-3.30pm Coffee and networking break 
3.30-4.30pm Session 4: Novel approaches to identify new therapies
Dr Teresa Cortes (LSHTM, chair)
Dr Gillian Tomlinson (UCL)
Calibrating a balanced immune response in tuberculosis
Dr Luiz Pedro Carvalho (Francis Crick Institute)
How to make "resistance-proof" antibiotics?
Prof Helen McShane (Oxford University)
Progress and challenges in TB vaccine development
Prof Paul Elkington (University of Southampton)
Investigation of TB in a bioengineered human granuloma model
4.30-4.45pm Summary, thanks and handover to UCSF