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The bespoke CRC labs include a radiochemistry research lab and the UCL Good Manufacturing Practice (GMP) Facility.
The construction of the state-of-the-art radiochemistry research lab was completed in 2010, and the GMP Facility became operational in 2016. Both facilities are housed in the Kathleen Lonsdale Building, allowing the research and production teams to work hand in hand and therefore, foster truly translational research.
Radiochemistry research lab
The radiochemistry research lab is designed to allow radiochemistry method development, automated radiotracer production for preclinical studies, translational nuclear imaging in human specimens.
Generous funding from HEFCE and the UCL Hospitals Biomedical Research Centre allowed the construction of a state-of-the-art facility.
Three shielded fume hoods and two research hot cells equipped with Scintomics synthesis modules are complemented by a dedicated quality control lab.
UCL GMP Facility
Custom-designed for the production of investigational diagnostic agents for imaging in man, the UCL GMP Facility specialises on the manufacturing of short-lived radiotracers as well as tracers for cutting-edge imaging techniques such as hyperpolarised MRI.
The facility houses a class C cleanroom with four Tema hot cells and two class A isolators. Tracer production is carried out on the Trasis AllinOne platform.
The dedicated quality control lab features Agilent and Shimadzu high performance liquid chromatography systems, integrated with Lablogic radiodetectors, an Agilent gas chromatography, radio TLC system and Endosafe equipment for pyrogen testing.
