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Dr Jose Prieto Garcia

Dr Jose Prieto Garcia

Lecturer B

Pharma & Bio Chemistry

UCL School of Pharmacy

Joined UCL
4th Apr 2005

Research summary

Current Research Lines:

  • Anti-inflammatory, anti-allergic and anticancer natural products with dual COX/LOX inhibition and targeted lipidomics.

  • Herb-Drug interactions.
  • Computational chemistry for the prediction of the bioactivity of complex mixtures of natural products and food supplements.

  • Direct NMR for the metabolomics of tinctures.

Past Research Lines:

Preclinical development of antiallergic food supplements, development of new NMR-based metabolomic strategies, Applying artificial intelligence to drug discovery.  Modulation of eicosanoid release by Traditional Chinese Medicines, 5-LOX inhibitors in skin inflammation, antioxidant and antinitrosative properties of natural products, and the ecological role of plant steroids. CB2 receptors and Rheumatoid Arthritis (with RVC).

Consultancy

  • Method development in QC of herbal products.
  • Evaluation of the pharmacological, nutraceutical and cosmeceutical aspects of innovative herbal active principles.

Teaching summary

My teaching duties include

Undergraduate Teaching includes:

  • Separation and Chromatography (MPharm Year 1).
  • Herbal Medicines in Community Pharmacy (MPharm Year 2).
  • Medicinal Natural Products (MPharm Option, Year 3).

Postgraduate Teaching (Master level):

  • Course Director of MSC in Medicinal Natural Products and Phytochemistry.
  • Module leader of Therapeutic Uses of Plants and Analytical Techniques in Pharmacognosy (MSC in Medicinal Natural Products and Phytochemistry).

Education

FHEA, |
Institute of Education
PGCLTHE, Education - Postgraduate | 2011
Universidad de Valencia
PhD, Pharmacology | 2001
Universidad de Valencia
Cert., Cancer Studies | 1998
Universidad de Valencia
Cert., Genetics and Medicine | 1996
Universidad de Valencia
MAS, Pharmacy | 1995
Universidad de Valencia
LDA, Pharmacy | 1993

Biography

Dr Jose M Prieto-Garcia is Lecturer B in the Department of Biological and Pharmaceutical Chemistry of the UCL School of Pharmacy. His teaching duties include under and postgraduate lectures on analytical chemistry (‘Chromatography’), ‘Management of Herbal Products and Food supplements in Community Pharmacy’, ‘Medicinal Cannabis’ and ‘Drug Discovery at the Nutrition-Pharmacology interface’ and the leadership of the MSC in Medicinal Natural Products and Phytochemistry.

Dr. Prieto-Garcia's research started at elucidating the effect of anti-inflammatory medicinal plants and natural products on enzymes of the arachidonate pathway using targeted lipidomics. This state-of-the-art research was developed during his PhD (2001, Universitat de Valencia, Spain) alternating with visits to world-class centres such as the Institute of Pharmaceutical Sciences (University of Tubingen, Tubingen, Germany) and the William Harvey Institute (Queen Mary University, London, UK). After his PhD, he was immediately appointed as Young Researcher of the EU funded project 'Insect Chemical Ecology' (INCHECO) to explore the biochemical interactions between plants and insects (2001-2004, Department of Bioorganic Chemistry, Universita degli Studi di Pisa, Italy) gaining a wide experience in phytochemical analysis. He afterwards joined the Centre for Pharmacognosy and Phytotherapy in April 2005 as a Postdoctoral Researcher on a European Union funded consortium developing standardised extracts of Cannabis for use in the treatment of migraine and rheumatoid arthritis. In 2006 he became Lecturer in Pharmacognosy of the Centre for Pharmacognosy and Phytotherapy. In 2012 he became the director of the MSC in Pharmacognosy (later renamed as MSC in Medicinal Natural Products and Phytochemistry).

Publications