UCL News


UCL in the News: Modified cells 'could fight cancer'

3 July 2007

Genetically modified skin cells could be used to fight a deadly childhood cancer, a study suggests.

Tests on mice found that they could be deployed to fight neuroblastoma - a cancer of specialised nerve cells, known as "neural crest cells" often in the abdomen or adrenal glands. …

A team lead by Dr Stephen Hart at the UCL Institute of Child Health found that injecting GM cells into the tumours appeared to both increase life expectancy and improve the body's ability to fight the cancer in the future. …

"The genetically modified cells are little factories, producing proteins - proinflammatory cytokines - which promote immune activity," Dr Hart said.

Channel 4 News