LMCB - Laboratory for Molecular Cell Biology

Spiros Makris's picture

Research Associate, Acton Lab


Europe PMC | PubMed | ORCID | Researchgate 

Twitter @SpirosMakris21


Research synopsis

The resolution of lymph node expansion and return to steady state is an unaddressed question, but perhaps understandably neglected since the immune cells migrate to the site of infection. Responsive lymph nodes need to expand both to accommodate thousands of naïve lymphocytes infiltrating and to provide additional space for their clonal proliferation in response to antigen. Lymph nodes undergo vast increases in organ size during adaptive immune responses and can undergo rapid and yet completely reversible remodeling countless times. My aim is to understand how homeostasis is regained as immune responses are resolved. Specifically, understand resident and recruited populations within the lymph nodes, and how cellular interactions drive tissue remodelling and the resolution of inflammation.


2017 | PhD, Respiratory Infections, Imperial College London, UK
2013 | Research assistant, NHLI, Imperial College London, UK
2011 | MSc, Molecular Medicine, University College London, UK
2010 | BSc, Biomedical Sciences, University of Essex, UK


2017 | British Society for Immunology Congress 2017 Bursary Award
2016 | British Society for Immunology Congress 2016 Bursary Award
2015 | Keystone Symposia Travel Bursary from the British Society for Immunology
2014 | British Society for Immunology Congress 2014 Bursary Award
2013 | Rosetrees Trust funding PhD project (M370)
2013 | British Society for Immunology Congress 2013 Bursary Award


European Research Council

Research themes

Cell migration
Tissue remodelling
Cell-cell interactions


Flow cytometry
Mass cytometry
Super-resolution microscopy
Light microscopy