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LMCB - MRC Laboratory for Molecular Cell Biology

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Research Synopsis

The resolution of lymph node expansion and return to steady state is an unaddressed question, but perhaps understandably neglected since the immune cells migrate to the site of infection. Responsive lymph nodes need to expand both to accommodate thousands of naïve lymphocytes infiltrating and to provide additional space for their clonal proliferation in response to antigen. Lymph nodes undergo vast increases in organ size during adaptive immune responses and can undergo rapid and yet completely reversible remodeling countless times. My aim is to understand how homeostasis is regained as immune responses are resolved. Specifically, understand resident and recruited populations within the lymph nodes, and how cellular interactions drive tissue remodelling and the resolution of inflammation.

Biography

2017 | PhD, Respiratory Infections, Imperial College London, UK
2013 | Research assistant, NHLI, Imperial College London, UK
2011 | MSc, Molecular Medicine, University College London, UK
2010 | BSc, Biomedical Sciences, University of Essex, UK
 

Awards

2017 | British Society for Immunology Congress 2017 Bursary Award
2016 | British Society for Immunology Congress 2016 Bursary Award
2015 | Keystone Symposia Travel Bursary from the British Society for Immunology
2014 | British Society for Immunology Congress 2014 Bursary Award
2013 | Rosetrees Trust funding PhD project (M370)
2013 | British Society for Immunology Congress 2013 Bursary Award
 

Funders

European Research Council

Research Themes

Cell migration, Tissue remodelling, Cell-cell interactions

Technology

Flow cytometry, Mass cytometry, Super-resolution microscopy, Light microscopy