The Henriques lab was established in 2013 to undertake research combining cell biology, optical physics and biochemistry. The group focuses on biological problems that cannot be addressed with current imaging technology, and thus aims to develop analytical, optical and biochemical approaches to address these questions.
In cell biology we aim to understand how viruses enter cells by probing and remodelling membranes, and what are the structural changes viruses undergo during cell-entry, uncoating and morphogenesis. To do so, we are developing new classes of fluorescent probes, high-speed cell friendly Super-Resolution (SR) methods and computational modelling approaches that, although designed to answer questions of interest in the lab, will have broad applications in cell biology research.
About the lab
Medical Research Council
Cytoskeleton and cell cortex, Signalling pathways, Cell-cell interactions, Membrane trafficking, Viral pathogens, Biophysics, Computational biology
Light microscopy, Super-resolution microscopy, Translational research, Electron microscopy