Centre for Inflammation and Tissue Repair

The aim of our research is to improve our understanding of the pathomechanisms of major debilitating and often fatal conditions, including acute respiratory distress syndrome, pulmonary infections, chronic obstructive pulmonary disease, asthma, bronchiectasis, interstitial lung diseases, sarcoidosis and fibrotic disorders of the lung and other organs, in the hope of developing future treatments.

The research programmes range from studies aimed at understanding disease pathways at the cellular, molecular, genetic, biochemical, physiological and pathological level, to clinical studies and studies focused on novel target identification for drug discovery.

CITR currently comprises around 35 staff members, including five principal investigators leading internationally competitive research programmes. We have extensive collaborative links with other leading academic centres and with industry and are also a major PhD training centre for junior scientists and physicians within the UK and beyond.

Our laboratories are well-equipped and our translational studies are underpinned by engagement with clinically active clinician scientists with well-characterized patient cohorts based within the UCLP network of hospitals, including University College Hospital (UCLH) and the Royal Free Hospital. 

Our research is supported by grants from the Wellcome Trust, the Medical Research Council, the British Lung Foundation, Arthritis Research UK, Asthma UK and via collaborative research alliances with industry.

The Centre for Inflammation and Tissue Repair (CITR) is part of the UCL Respiratory collaborative network with close links to The Lungs for Living Research Centre (L4L)  and The Centre for Respiratory Biology. 

Head of Centre

• Professor Rachel Chambers

Principal Investigators

• Professor Jeremy Brown
• Professor John Hurst
• Professor Robin McAnulty (Emeritus)
• Professor Joanna Porter
• Professor Marc Lipman