Diseases & treatments We develop vaccines and use cell and gene therapy to treat immune-related conditions and induce tolerance in organ tranplantation and tissue engineering. Cancer Immunotherapy of cancer can achieve durable tumour regression in patients who do not respond to chemo- and radiation therapy. Chronic infections Chronic infections can impair the fitness of the immune system and thus allow unhindered virus persistence and replication. Autoimmune diseases Faulty genes can cause rare diseases such as immunodeficiency, haemophilia and lysosomal storage disease. Transplantation We aim to achieve kidney and liver transplantation without the need for life-long immune suppression. Inherited diseases Faulty genes can cause rare diseases such as immunodeficiency, haemophilia and lysosomal storage disease. Tissue repair Defective tissue repair in response to inflammation and damage can lead to scarring and fibrosis.