Institute of Immunity and Transplantation


NK T-cell lymphoma


Pioneering research

Each month we will provide an update of an ongoing research project on PID at the Royal Free.

Current research projects

With help and agreement from patients, research at the Royal Free investigates the fundamental causes of PID, the complications and the long-term management of these lifelong diseases.

Current projects:

  • Cognitive Behavioural Therapy (CBT) in PID
  • UKPIN/ESID registry: Long-term accumulation of clinical data in Registry) family study (to help identify genetic defects causing PID.
  • Prion study: Long-term national study to assess risk of patients being 'infected' by prions in blood products.
  • JMF QoL study: Measuring improvements in quality of life after immunoglobulin therapy.
  • CGD studies: Investigating chemical interactions in cells from CGD patients.
  • BioREsources study: Collecting DNA from patients to search for new genetic causes of PID.
  • STILPAD Study: Multi-centre EU study documenting the effect of various treatments on lung inflammation in PID.
  • Gammatrack: An observational study on effects of regular Flebogamma.
  • Grifols observational study on effects of Flebogamma
  • Respiratory study: Diagnosing and monitoring types of lung infection.
  • CMV study: Investigating the role of cytomegalovirus (CMV) in bowl and liver inflammation.
  • Liver study: Testing whether toxins from the bowel can cause liver disease in PID.