SIREN (Sarscov2 Immunity & REinfection EvaluatioN)

Impact of detectable anti-SARS-COV2 on the subsequent incidence of COVID-19 in healthcare workers

Project Summary

SIREN is an NIHR urgent public health priority study which aims to determine if prior SARS-CoV-2 infection in health care workers confers future immunity to re-infection.

It will also allow us to estimate the prevalence of SARS-CoV-2 infection in healthcare workers and use this information to determine wider staff testing.

NHS staff are asked to provide regular swabs (fortnightly) for PCR testing and blood samples (monthly) for serology testing.

Links to other research

Other research from the UCL Centre for Clinical Research in Infection and Sexual Health

Other research from IGH on Prevention, Public Health, Population Health, COVID-19 and Infectious Diseases

Other research from IGH in the UK

Project information

Dates: September 2020 to September 2022

Status: Current

IGH lead: Dr Alejandro Arenas-Pinto

Lead organisation: Public Health England

Project lead: Dr Susan Hopkins

Partners: Public Health England, Public Health Agency, Public Health Scotland, Public Health Wales, Central and North West London NHS Foundation Trust

Location: UK

Funding: Department of Health and Social Care

Contact: Rebecca Matthews (rebecca.matthews5@nhs.net), Paulina Prymas (paulina.prymas@nhs.net) and Abigail Severn (a.severn@nhs.net)

Research team

Dr Alejandro Arenas-Pinto
Dr Richard Gilson
Rebecca Matthews
Paulina Prymas
Abigail Severn

Resources

SIREN study page on PHE website