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RESPOND

The International Cohort Consortium of Infectious Disease

Project Summary 

The International Cohort Consortium of Infectious Disease (RESPOND) is a non-interventional, non-randomized, open-label, multi-cohort observational study.

The aim of RESPOND is to build an innovative, flexible and dynamic cohort consortium for the study of infectious diseases, including HIV and people at risk for HIV, as a generic structure for facilitating multi stakeholder involvement.  This consortium builds upon the outstanding collaborative work in HIV cohort studies that has taken place in Europe and beyond over the last 20 years and which has provided crucial information contributing to the improvement in the lives of HIV-positive individuals.

RESPOND will continue with a rigorous approach to answering questions with robust and reliable scientific methodologies as well as having the flexibility and willingness to answer the most important questions of interest to the infectious diseases research community.

RESPOND will be based on an extremely successful and highly experienced existing infrastructure, which will be adapted and expanded – including an inclusive network of clinics and cohorts and utilizing the operational infrastructure used for EuroSIDA, INSIGHT and other key studies, based at CHIP since 1994.

In 2018, RESPOND enrolled more than 29,000 patients into its core module, from 17 contributing cohorts. 


Key Project Information

Dates: 01/01/17 – 31/12/20

Status: Current

UCL lead/Principal Investigator: Professor Amanda Mocroft

Lead organisation: CHIP, Department of Infectious Diseases, Rigshospitalet, University of Copenhagen

Partners: AIDS Therapy Evaluation in the Netherlands Cohort (ATHENA), The Australian HIV Observational Database (AHOD), Austrian HIV Cohort Study (AHIVCOS), CHU Saint-Pierre, EuroSIDA Cohort, Frankfurt HIV Cohort Study, Georgian National AIDS Health Information System (AIDS HIS), Italian Cohort Naive Antiretrovirals (ICONA), Modena HIV Cohort, Nice HIV Cohort, PISCIS Cohort Study, Royal Free Hospital Cohort, San Raffaele Scientific Institute, Swedish InfCare HIV Cohort, Swiss HIV Cohort Study (SHCS), University Hospital Bonn, University Hospital Cologne

Location: Europe, Australia

Funding: The International Cohort Consortium of Infectious Disease (RESPOND) has received funding from ViiV Healthcare LLC and Gilead Sciences. Additional support has been provided by participating cohorts contributing data in-kind and/or statistical support: Austrian HIV Cohort Study (AHIVCOS), The Australian HIV Observational Database (AHOD), CHU Saint-Pierre, University Hospital Cologne, The EuroSIDA cohort, Frankfurt HIV Cohort Study, Georgian National AIDS Health Information System (AIDS HIS), Modena HIV Cohort, San Raffaele Scientific Institute, Swiss HIV Cohort Study (SHCS), Royal Free HIV Cohort Study

Contact: respond.rigshospitalet@regionh.dk

Websitewww.chip.dk/Studies/RESPOND/