Iron deficiency anaemia affects almost half of the world’s pregnant population and causes maternal mortality and long-lasting adverse health outcomes. Inadequate weight gain and micronutrient intakes during pregnancy are associated with low birthweight and maternal mortality. 20% of maternal deaths are directly related to anaemia and over half of the world’s maternal deaths caused by severe anaemia occur in South Asia. Our research seeks to understand and address the drivers of iron deficient anaemia in low-income countries and further the evidence base about what works, how and in what context.
The primary objective of the CAPPT trial is to assess if providing a tailored dosage of oral iron-folic acid supplementation along with personalised nutrition education and counselling supported by PLA women's groups increases haemoglobin levels at 28 weeks of pregnancy, compared with haemoglobin levels in women who have PLA women's groups only in their communities and with women who have access to routine antenatal care only (control).
The interventions will be tested through a non-blinded cluster-randomized controlled trial in parallel in India and Nepal with concurrent process evaluations.