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Comprehensive Anaemia Program and Personalised Therapies (CAPPT)

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Project Summary 

Iron deficiency anaemia affects almost half of the world’s pregnant population with 20% of maternal deaths directly related to anaemia. Over half of the world’s maternal deaths caused by severe anaemia occur in South Asia. Inadequate weight gain and micronutrient intakes during pregnancy are associated with low birthweight and maternal mortality. Our research seeks to understand and address the drivers of iron deficient anaemia in low-income countries and further the evidence base about what works, how and in what context.

In Nepal the CAPPT trial will evaluate the effect of two home-counselling visits to pregnant women with tailored iron folic acid supplementation, plus monthly participatory learning and action women’s groups, on haemoglobin levels at 28-32 weeks of pregnancy. 
In India the CAPPT trial will evaluate the effect of two home counselling visits to pregnant women with tailored iron folic acid supplementation on haemoglobin levels at 28-32 weeks of pregnancy. 

Interventions will be tested through a non-blinded cluster-randomized controlled trial with concurrent process evaluation.  


Key Project Information

Dates: 1st November 2018 - 31st October 2021

Status: Current

UCL lead/Principal Investigator: Dr Sara Hillman (UCL Institute for Women’s Health)

Partners: HERD NGO/HERD International, AIIMS, New Delhi and LSHTM

Location: Nepal, India and the UK

Funding: MRC/ Newton Fund, Indian DBT and UCL GEO

Contact: Sara Hillman (sara.hillman@ucl.ac.uk)

Research Team

Institute for Global Health
Joanna Morrison, Naomi Saville, Andrew Copas, Jolene Skordis

LSHTM
Dr Phil James and Dr Helen Harris Fry 

Nepal
Dr Sushil Baral and Dr Chandani Kharel (HERD International)

India
Dr Vatsla Dadhwal; Dr Vandana Jain, Dr Aparna Sharma, Gurdeep Kaur and Dr Shashi Kant (AIIMS)


Publications

Assessing food-based strategies to address anaemia in pregnancy in rural plains Nepal: a mixed methods study (Cambridge Core, October 2022)

Addressing anaemia in pregnancy in rural plains Nepal: A qualitative, formative study (Maternal and Child Nutrition, July 2021)

Comprehensive Anaemia Programme And Personalized Therapies (CAPPT): Protocol For A Cluster-Randomised Controlled Trial Testing The Effect Women’s Groups, Home Counselling And Iron Supplementation On Haemoglobin In Pregnancy In Southern Nepal (Research Square, June 2021)

Health worker perspectives on access to antenatal care in rural plains Nepal during the COVID-19 pandemic (PLOS one 2023)