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A Phase 3b, Randomised, Open-Label Study to Evaluate the Safety and Efficacy of Switching from Regimens Consisting of ABC/3TC plus a Third Antiretroviral Agent to the E/C/F/TAF Fixed-Dose Combination (FDC) in Virologically-Suppressed HIV-1 Infected Adult Subjects
Project Summary
This study will evaluate the efficacy of switching to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) fixed-dose combination (FDC) relative to continuing on a baseline regimen consisting of abacavir/lamivudine (ABC/3TC) plus a 3rd antiretroviral agent in maintaining HIV-1 virologic suppression.
Key Project Information
Dates: September 2016 - May 2018 (completed)
UCL lead/Principal Investigator: Dr Laura Waters
Partners: Central and North West London NHS Foundation Trust
Location: Global
Funding: Gilead Sciences
Contact: mmc-research-cnwl@nhs.net
- Research Team
Dr Alejandro Arenas-Pinto
Marzia Fiorino
Dr Lewis Haddow