Institute of Epidemiology & Health Care


RESPECT-21 Reorganising specialist Cancer Surgery for the 21st Century

This project is studying the centralisation of specialist surgical pathways for four cancers across two health care systems: London Cancer (a network of providers across North Central and North East London, and West Essex; population 3.2m) and Greater Manchester Cancer (covering Greater Manchester and East Cheshire; population 3.1m). The research team is formed of clinicians, patients, and academics from London (UCL and London Cancer) and Manchester (University of Manchester and Greater Manchester Cancer).   The research is combining quantitative and qualitative methods to analyse how the centralisations were planned and implemented, and the impact of the changes on organisation and delivery of care, clinical outcomes, patient experience, and cost-effectiveness.  It is also analysing patient, professional, and public preferences for changes of this kind. In doing so, the study will address a number of important gaps in the evidence on centralising specialist cancer surgery, addressing key priorities highlighted in the Five Year Forward View. In addition, it will build on methods developed by the team in conducting high impact research on other forms of major system change.

Principal Investigator: Professor Naomi Fulop

Project Staff/Co-investigators: 

Professor Ruth Boaden, University of Manchester

Mr John Hines, University College London Hospital NHS Foundation Trust

Ms Rachael Hunter, University College London

Professor Steve Morris, University of Cambridge

Professor Kathy Pritchard-Jones, University College London

Dr Angus Ramsay, University College London

Mr David Shackley, Greater Manchester Cancer


Dr Georgia Black, University College London

Dr Caroline Clarke, University College London

Dr Maria Melnychuk, University College London

Dr Catherine Perry, University of Manchester

Dr Laura Vellejo-Torres, University College London

Dr Cecilia Vindrola, University College London

Patient collaborators:

Veronica Brinton, Patrick Fahy, and John Sandell

Clinical/organisational collaborators:

Mr Ravi Barod, Royal Free London NHS Foundation Trust

Dr Afsana Bhuiya,  University College London Hospital NHS Foundation Trust

Professor Mark Emberton, University College London

Ms Claire Levermore,  University College London Hospital NHS Foundation Trust

Mr Satish Maddineni, Salford Royal NHS Foundation Trust

Ms Caroline Moore,  University College London Hospital NHS Foundation Trust

Professor Muntzer Mughal,  University College London Hospital NHS Foundation Trust

Mr Dipankar Mukherjee, Barking, Havering and Redbridge Hospital NHS Trust

Ms Maxine Tran, Royal Free London NHS Foundation Trust

Mr Jonathan Vickers, Salford Royal NHS Foundation Trust


Michael Aitchison,  Sarah Darley, David Holden, Colin Jackson

Remembering our colleague Neil Cameron:

Sadly one of our PPI colleagues Mr Neil Cameron died on 15th May 2017. Neil contributed a great deal to the study, from the development of the proposal, in particular providing essential feedback on our research questions in relation to patient experience, through to the work of the study to date. We will continue to acknowledge Neil’s contribution to our study in any outputs that we make.

Funder: National Institute for Health Research Health Services and Delivery Research Programme

Start Date: 2015

Duration: 5 years

Contact: Prof Naomi Fulop (Chief Investigator): n.fulop@ucl.ac.uk Pei Li Ng (Project Manager): pei.ng@ucl.ac.uk