UCL Great Ormond Street Institute of Child Health


Great Ormond Street Institute of Child Health

Miss Lola Solebo

Miss Lola Solebo

NIHR Clinician Scientist and Honorary Consultant

Population, Policy & Practice Dept

UCL GOS Institute of Child Health

Joined UCL
7th Aug 2013

Research summary

My interest is in the determinants of outcome for children with eye disease, and the translation of these findings to practice and policy. 


This national observational longitudinal study has established a unique cohort of children undergoing cataract surgery, and is supported by a clinical research network of over 160 consultant ophthalmologists, the British Isles Congenital Cataract Interest Group (BCCIG). Worldwide, cataract is the leading cause of avoidable childhood blindness. 
Our work has shown that despite the early promises of artificial lens implants for these children, visual outcomes are not improved and adverse events are more common than with standard treatment. These and other findings have impacted on national practice, have been used internationally as a benchmark, and by the Public Health England National Screening Committee (PHE NSC) in their review of Newborn and Infant screening

Childhood Vision Screening

Findings from our NSC commissioned systematic review into childhood vision screening informed the PHE Childhood Vision Screening programme. 
I am also a member of the PHE Vision Screening Advisory Group and contributed to the development of national resources to support commissioning and delivery (launched October 2017) 

Childhood Uveitis Signs and Symptoms Study (ChUSS)

This study aims to develop imaging based and patient reported disease metrics to stratify a rare, potentially blinding childhood inflammatory eye disease: Uveitis
For children with uveitis, the current tools used in clinical assessment need improvement.
We are going to use new imaging technologies and self reporting instruments to assess how children are affected by disease.
We are also establishing a multicentre longitudinal cohort study, which will also allow us to identify the determinants of outcome.
This work is supported by a patient steering group, and a multi-disciplinary national group of specialists (the Paediatric Ocular Inflammation Group). 


I fell in love with Epidemiology at medical school after hearing about John Snow, and fancied myself as a future medical detective. 

I was a PhD student at UCL ICH, and I’ve stayed because of the warmth, generosity and cross-disciplinary nature of my department, and the quality and impact of our output – as well as the strong relationships between ICH, GOSH and the other UCL partners such as the NIHR Biomedical Research Centre at Moorfields.

My husband Mark and I are parents to two elemental forces disguised as human girls. https://medscilife.org/stories/dr-lola-solebo/