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Prof Waseem Qasim

Prof Waseem Qasim

Professor of Cell and Gene Therapy

Infection, Immunity & Inflammation Dept

UCL GOS Institute of Child Health

Joined UCL
1st Sep 2003

Research summary

Development and application of genome editing and gene based therapies.
  • Application of T lymphocytes for cellular immunotherapy, including CAR T cells.
  • Translational immunotherapies,  from bench to bedside and first-in-human trials
  • Clinical trials for 'of the shelf' genome edited T cells
  • Diagnosing and treating immune disorders by haematopoietic stem cell transplantation and gene based therapies.
  • Studies of T cell responses to viruses for anti-viral cell therapies
  • Investigating genome editing by CRISPR/Cas9 and base editors to correct inherited diseases.
  • Universal cells: genome editing to overcome HLA barriers for regenerative medicine (Human pluripotent stem cells).

  • Clinical gene therapy for skin disorders such as Netherton's syndrome and Epidermolysis Bullosa.
  • Regulatory, ethics and safety monitoring

Teaching summary

Previous UCL teaching has included:
1.  MSc Clinical Cell & Gene Therapy, module organiser and lecturer
2.  Lecturer MSc Human Genetics, Disease to gene therapy
3.  Lecturer on MRes in Biomedicine course,Gene Therapy for Immunodeficiency 
4.  Lecturer on MSc in Paediatrics course,Cell and gene therapy for cancer 

Active PhD supervisor and examiner

Education

University College London
Doctorate, Doctor of Philosophy | 2003
Royal College of Paediatrics and Child Health
Doctorate, Member of the Royal College of Paediatrics and Child Health | 1997
Royal College of Physicians
Doctorate, Member of the Royal College of Physicians | 1996
Newcastle University
Doctorate, Bachelor of Medicine/Bachelor of Surgery | 1993
University of Newcastle upon Tyne
Doctorate, Bachelor of Medical Science | 1993

Biography

2003-2007: Leukaemia Research Fund clinician scientist/lecturer in Paediatric Immunology/ Bone marrow transplantation, Institute of Child Health & Great Ormond Street Hospital, London

2007-2012: Senior Clinical Lecturer, Institute of Child Health & Great Ormond Street Hospital, London

2012- 2015: Reader in Cell & Gene Therapy, Institute of Child Health & Great Ormond Street Hospital, London

2015- 2021: NIHR Professor of cell and gene therapy developing next generation T cell gene therapies.

2021- NIHR senior investigator, UCL Professor of cell and gene therapy

Publications