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Prof Waseem Qasim
Professor of Cell and Gene Therapy
Infection, Immunity & Inflammation Dept
UCL GOS Institute of Child Health
- Joined UCL
- 1st Sep 2003
Research summary
Development and application of genome editing and gene based therapies.
- Application of T lymphocytes for cellular immunotherapy, including CAR T cells.
- Translational immunotherapies, from bench to bedside and first-in-human trials
- Clinical trials for 'of the shelf' genome edited T cells
- Diagnosing and treating immune disorders by haematopoietic stem cell transplantation and gene based therapies.
- Studies of T cell responses to viruses for anti-viral cell therapies
- Investigating genome editing by CRISPR/Cas9 and base editors to correct inherited diseases.
- Universal cells: genome editing to overcome HLA barriers for regenerative medicine (Human pluripotent stem cells).
- Clinical gene therapy for skin disorders such as Netherton's syndrome and Epidermolysis Bullosa.
- Regulatory, ethics and safety monitoring
Teaching summary
Previous UCL teaching has included:
1. MSc Clinical Cell & Gene Therapy, module organiser and lecturer
2. Lecturer MSc Human Genetics, Disease to gene therapy
3. Lecturer on MRes in Biomedicine course,Gene Therapy for Immunodeficiency
4. Lecturer on MSc in Paediatrics course,Cell and gene therapy for cancer
Active PhD supervisor and examiner
Education
- University College London
- Doctorate, Doctor of Philosophy | 2003
- Royal College of Paediatrics and Child Health
- Doctorate, Member of the Royal College of Paediatrics and Child Health | 1997
- Royal College of Physicians
- Doctorate, Member of the Royal College of Physicians | 1996
- University of Newcastle upon Tyne
- Doctorate, Bachelor of Medical Science | 1993
- Newcastle University
- Doctorate, Bachelor of Medicine/Bachelor of Surgery | 1993
Biography
2003-2007: Leukaemia Research Fund clinician scientist/lecturer in Paediatric Immunology/ Bone marrow transplantation, Institute of Child Health & Great Ormond Street Hospital, London
2007-2012: Senior Clinical Lecturer, Institute of Child Health & Great Ormond Street Hospital, London
2012- 2015: Reader in Cell & Gene Therapy, Institute of Child Health & Great Ormond Street Hospital, London
2015- 2021: NIHR Professor of cell and gene therapy developing next generation T cell gene therapies.
2021- NIHR senior investigator, UCL Professor of cell and gene therapy
