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UCL Great Ormond Street Institute of Child Health

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Prof Christine Kinnon

Prof Christine Kinnon

Professor of Molecular Immunology

Infection, Immunity & Inflammation Dept

UCL GOS Institute of Child Health

Joined UCL
1st Aug 1986

Research summary

My research has involved the elucidation of the molecular and cellular defects in inherited immunodeficiency disorders which has resulted in our identification of several disease causing genes. We are now investigating the functions of the protein products of these genes, in both health and disease. We are translating the results of this basic research into new and improved strategies for treatment, principally by the development of techniques for the cure of these disorders by somatic gene therapy techniques.

We have initiated phase I clinical trials for the treatment of X-linked severe combined immunodeficiency (SCID), adenosine deaminase (ADA) deficient SCID, X-linked chronic granulomatous disease (CGD) and Wiskott-Aldrich syndrome using gene therapy techniques. 

I am currently the UCL Academic Lead for the Zayed Centre for Research into Rare Disease in Children, a joint project between UCL, GOSH and the GOSH Charity. 

Teaching summary

Student Supervision: I have supervised research students at BSc, MSc, MPhil and PhD level, seeing more than 20 PhD students to completion.

Lecturing: I have been responsible for teaching on a variety of under-graduate (UG) and post-graduate (PG) courses within and external to UCL throughout the year, including a number of European Summer Schools. 

Leadership in Teaching:  Between 2011 and 2018 I was Deputy Director (Education) at GOS ICH and Vice-Dean Education in the Faculty of Population Health Sciences at UCL, responsible for the education and training of over 1,000 postgraduate taught and research students across a wide range of health-related disciplines. In 2011, I established, and subsequently directed, the world’s first MSc programme in Cell and Gene Therapy at GOS ICH.  

 

Education

University College London
PhD, Immunology | 1984
University of Newcastle upon Tyne
BSc Hons, Biochemistry | 1978

Biography

Education/Qualifications
1978 BSc (Hons) Biochemistry,University of Newcastle-upon-Tyne
1984 PhD Immunology, Imperial Cancer Research Fund/University College London

Professional History 
1978-1980 Scholarship student, University of California at San Diego, La Jolla, California, USA
1984-1986 Life Sciences Research Fund Post-Doctoral Fellow, California Institute of Technology, Pasadena, California, USA
1986-1991 Lecturer in Immunology and Genetics, GOS ICH
1991-1995 Senior Lecturer in Molecular Immunology, GOS ICH
1995-1998 Reader in Molecular Immunology, GOS ICH
1998 to date  Professor of Molecular Immunology, GOS ICH
2009 to date: Hugh Greenwood Professor of Immunology

Leadership Roles: 
1995-2014 Head of Molecular Immunology Unit, GOS ICH
2004-2014    Head of Infection and Immunity Theme, GOS ICH
2009-2018 Deputy Director, Education, GOS ICH
2011-2017 Programme Director MSc Cell and Gene Therapy
2011-2018 Vice Dean Education, FPHS
2013-2015      Faculty Tutor, FPHS
2012 to date: UCL Academic Lead Zayed Centre for Research into Rare Diseases in Children (ZCR)
2018 to date: Director of Development, GOS ICH
2019 to date:   Deputy Head of Infection, Immunity and Inflammation Programme, GOS ICH






Publications