Departmental Seminar

05 February 2020, 3:00 pm–4:00 pm

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Design Strategies for Cluster-Nanocarrier beads for MRI contrast agents Prof. Sarah Stoll, Georgetown University

This event is free.

Event Information

Open to

UCL staff | UCL students






Gemma Davies

There are many opportunities for new MRI contrast agents, whether to replace Gd chelates, or to probe the utlility of nanomaterials for biomedical imaging. Our work has brought together highly paramagnetic clusters paired with nanocarriers made of polymers (both hydrophilic and hydrophobic), as well as silica (various pore structures). By using a nanocarrier, clusters which have been underexplored because of speciation concerns exhibit impressive relaxivities. The nanocarrier also plays an important role as it controls the immediate environment of the highly relaxing clusters but also provides the biological interface. This talk will provide a review of the advantages and disadvantages of a range of cluster-nanocarrier systems that we have developed for MRI contrast.

About the Speaker

Prof. Sarah Stoll, Georgetown University

Prof. Stoll received her BA from Smith College (1988) and PhD from U. C. Berkeley (1993), where she worked with Angy Stacy. She was a post-doctoral fellow with Andrew Barron before joining Georgetown University in 2002. She was promoted to full professor in 2019 and is currently on sabbatical in the Inorganic Chemistry Laboratory at the University of Oxford