UCL Institute of Cardiovascular Science


Centre for Translational Genomics 

Variation in the sequence of the human genome alters underlie differences in physiology and metabolism as well as susceptibility to common and rare cardiovascular disorders.

Work in the Centre for Translational Genomics seeks to identify the relevant genetic variants and to use these, in conjunction with other –omic technologies (e.g. proteomics and metabolomics), to screen and predict risk of future disease, improve diagnosis, delineate disease and patient subtypes, and to understand causes of cardiovascular and related disorders.

The work benefits from access to large population and patient cohorts both within and beyond the Research Department of Population Science and Experimental Medicine, through international consortia and collaborations. There is an increasing emphasis within the centre on statistical genetics, computational biology and bioinformatics, as well as close links with the UCL Institute of Health Informatics with where the Centre’s Research groups are housed.