Using advanced phenotyping and multi-omic techniques to stratify disease and develop personalised therapeutic approaches in childhood inherited and rare cardiovascular disease
The UCL Centre for Paediatric Inherited and Rare Cardiovascular Disease is a multidisciplinary clinical and translational research group focussed on understanding disease mechanisms and investigating novel therapeutic approaches for genetic and rare cardiovascular disorders in childhood. The Centre is based in the Zayed Centre for Research into Rare Diseases in Children and has close links with the internationally recognised clinical UK National Paediatric Pulmonary Hypertension service and the Centre for Inherited Cardiovascular Diseases at Great Ormond Street Hospital.
The Centre’s research portfolio is underpinned by advanced phenotyping, multi-omic characterisation and clinical outcomes and data linkage research methodologies, with the aim of developing personalised therapeutic strategies. Research is supported by grants and fellowships from the Medical Research Council (MRC), British Heart Foundation (BHF), Action Medical Research (AMR), National Institute of Health Research (NIHR), Great Ormond Street Hospital Children’s Charity (GOSHCC), the Dinosaur Trust, Max’s Foundation and the GOSH and UCL Biomedical Research Centres.
Lead: Dr Juan Pablo Kaski
Group members: Dr Shahin Moledina, Dr Gabrielle Norrish, Dr Olga Boleti, Dr Elena Cervi, Dr Luke Starling, Dr Sadia Quyam, Ella Field, Lynsay MacDonald, Eleni Tamvaki, Annabelle Barnes, Imogen Heenan
- Paediatric Inherited Cardiovascular Diseases
- Paediatric Pulmonary Hypertension
Centre for Paediatric Inherited and Rare Cardiovascular Disease
Department of Children's Cardiovascular Disease, UCL Institute of Cardiovascular Science
3rd Floor, Zayed Centre for Research into Rare Disease in Childhood
20 Guilford Street
London WC1N 1DZ