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Regulatory Genomics Datasets

Cottone et al. Inhibition of histone H3K27 demethylases inactivates brachyury (TBXT) and promotes chordoma cell death, Cancer Research, 2020.
ChIP-seq for H3K27me3, H3K27ac, H3K4me3 and H3K9me3 and RNA-seq in chordoma cells treated with KDM6A/6B inhibitors.
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Śledzińska et al. Regulatory T cells restrain IL-2- and Blimp-1-dependent acquisition of cytotoxic function by CD4+ T cells, Immunity, 2020.
Microarray data for CD4+ T cells from mouse tumours and lymph nodes.
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Beltran et al. G-tract RNA removes Polycomb Repressive Complex 2 from genes, Nature Stuctural and Molecular Biology, 2019.
iCLIP for SUZ12, FUS and HNRNPC input samples.
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Anandagoda et al. microRNA-142-mediated repression of phosphodiesterase 3B critically regulates peripheral immune tolerance, Journal of Clinical Investigation, 2019.
ChIP-seq for Foxp3 in murine Th1 and iTreg cells.
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Soderquest et al. Genetic variants alter T-bet binding and gene expression in mucosal inflammatory disease. PLOS Genetics, 2017.
ChIP-seq for T-bet in individuals heterozygous for inflammatory disease-associated genetic variants. Datalink

Hertweck et al. T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex. Cell Reports, 2016.
ChIP-seq for RNA pol II, P-TEFb and H3K4me3 in human Th1 and Th2 cells,  T-bet, Med1, Aff4, Brd4 and RelA in human Th1 cells, P-TEFb, Med1, Aff4, Brd4 and RelA in mouse WT and T-bet-/- Th1 cells, T-bet, P-TEFb, Med1, Aff4, Brd4 and RelA in EL4 cells with and without T-bet, RNA-seq in human Th1 and Th2 cells.
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Beltran et al. The interaction of PRC2 with RNA or chromatin is mutually antagonistic. Genome Research, 2016.
iCLIP for PRC2, FUS and HnRNP C, RNA-seq in WT and Ezh2-/- ES cells, ChIP-seq for Ezh2 and Suz12 in WT and Ezh2-/- ES cells, ChIP-seq for Suz12 and p300 with and without RNase A treatment.
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Gunnell et al. RUNX super-enhancer control through the Notch pathway by Epstein-Barr virus transcription factors regulates B cell growth. Nucleic Acids Research, 2016.
ChIP-seq for EBV EBNA2 in lymphoblastoid cells.
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Ramasubramanyan et al. Epstein-Barr virus transcription factor Zta acts through distal regulatory elements to directly control cellular gene expression. Nucleic Acids Research, 2015.
RNA-seq of B cells with and without EBV Zta expression.
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Vlachogiannis et al. The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis. Cell Reports, 2015.
MethylC-Seq of wild-type and Dnmt3LA/A 1dpp prospermatagonia.
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Bouwman et al. Human immunodeficiency virus Tat associates with a specific set of cellular RNAs. Retrovirology, 2014.
Microarray analysis of HIV Tat and Ago2 RNA IP and gene expression microarray analysis of T cell lines expressing HIV Tat and of primary T cells infected with HIV. Datalink

Gokmen et al. Genome-Wide Regulatory Analysis Reveals T-bet Controls Th17 Lineage Differentiation through Direct Suppression of IRF4. J Immunol. 2013.
ChIP-Seq of T-bet in mouse WT and Tbx21-/- Th1 cells  
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McClellan et al. Modulation of enhancer looping and differential gene targeting by epstein-barr virus transcription factors directs cellular reprogramming. PLoS Pathogens 2013.
ChIP-Seq of EBV EBNA2 and EBNA3 in the MutuIII Burkitt’s lymphoma line 
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Kanhere et al. T-bet and GATA3 orchestrate Th1 and Th2 cell differentiation through lineage-specific targeting of distal regulatory elements. Nature Communications 2012.
ChIP-Seq of T-bet and GATA3 in human Th1 and Th2 cells Gene expression microarray analysis of Thp, Th1 and Th2 cells from WT, Tbx21-/- and Gata-3 fl/fl x Tnfrsf4-Cre mice 
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Kanhere et al. Short RNAs are transcribed from repressed Polycomb target genes and interact with Polycomb Repressive Complex-2. Mol Cell 2010.
Gene expression microarray analysis of short ncRNAs in human T cells ChIP-Chip of histone modifications and RNA Pol II in human T cells 
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Jenner et al., The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes. Proc. Natl. Acad. Sci. USA 2009.
ChIP-Chip of T-bet and GATA3 in human Th1 and Th2 cells. Gene expression microarrays analysis of human Th1 and Th2 cells, and in murine Tbx21-/- /Ifng-/- T cells transduced with T-bet-RV or GFP-RV 
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