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UCL Department of Biochemical Engineering

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Vax Hub Platform Funding

Platform funding forms part of the Hub’s vision including knowledge transfer and ensuring that results translate to UK and LMIC vaccine markets.

Vax-Hub Feasibility Studies

In June 2020, the Vax-Hub launched a call for proposals for feasibility studies aligned to its aims and primarily of benefit to low- and middle-income countries (LMICs). We are pleased to announce that following our review process, seven projects were awarded funding.

PartnersProject title
Phenotypeca Ltd and University of Oxford Improving VLP vaccine production from baker's yeast  
University of Leeds and CPI Scale-up of bioproduction process in Pichia pastoris of a stabilised VLP vaccine candidate for poliomyeletis 
Vironova and UCLValidation of the MiniTEM system as an analytical quality control tool for vaccine and viral vector manufacturing 
University of Teesside 

The application of mass spectrometry approaches to profile, monitor and localise host cell protein products in adenovirus-based vaccine manufacture 

Hilleman Labs and UCLDevelopment and technology Transfer of optimised downstream process for purification of group B streptococcus polysaccharides by using microscale chromatography 
PT BioFarma and UCL 

Optimisation of upstream process for recombinant COVID-19 expressed in Pichia pastoris 

University of Oxford and UCL COVID-19 vaccine formulation  

Vax-Hub Interaction Vouchers

In February 2020, the Vax-Hub launched a call for proposals for interaction vouchers to support or encourage collaboration between its academic and industrial partners. We are pleased to announce that following our review process, six projects were awarded funding. 

PartnersProject title
Hilleman Labs and UCLEstablishing the use of microscale chromatography-for downstream process optimization of Group B streptococcus polysaccharides
Phenotypeca Ltd and University of OxfordExploiting the genetic diversity of Saccharomyces cerevisiae for VLP production

Sartorius Stedim Biotech and University of Oxford

Cost of goods evaluation of adenovirus-based vaccine against Coronavirus
Sartorius Stedim Biotech and University of OxfordImproving scalability and productivity of an adenovirus-based vaccine against Coronavirus

Univercells, University of Leeds and UCL

Proof of principle synthesis of polio virus-like particles in an E. coli cell-free manufacturing platform
Vironova and UCLMiniTEM analysis: characterisation of Viral Vaccines, Vectors and VLPs

Vax-Hub membership

Platform funding has been awarded to members of the Vax-Hub Users Group only. If you are not currently a member of the Hub but would be interested in joining to access this and other Hub benefits, please contact vaxhub@ucl.ac.uk