UCL Department of Biochemical Engineering


Successful Biomaterial Transfer

This course considers the nature of fluid flow in pipework and applies this to packed column chromatography systems. The means of calculating flow regimes and frictional losses in pipework are presented, and then used to determine design requirements for packed chromatography column systems.

Course Overview

  • Introduction to Chromatographic Systems
  • What you will Learn
  • Predicting Flow Characteristics in Pipework
  • Calculating Heads in a Pipework System
  • Predicting Flow in Packed Columns
  • Estimating Pressure Drops in Packed Beds
  • Appraisal
  • Course Summary

What you will learn

By successfully completing this course, you will be able to:

  • Understand the differences between turbulent flow and laminar flow
  • Determine the flow regime present by simple calculations
  • Calculate the head losses in a pipework system
  • Calculate the frictional losses in a pipework system
  • Correctly specify pump requirements for a system
  • Estimate pressure drop down a packed chromatography column
  • Analyse and design a complete chromatography system based on fluid flow
  • Gain insights to practical process considerations

Sample pages

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