UCL Division of Medicine
News and Events
Anna Rose, Daniel Marks, Stephen Morris-Jones, Aroon Hingorani
“ When is a contaminant not a contaminant?”
Case: Staphylococcus lugdunensis septic arthritis and epidural abscess in a patient on etanercept for rheumatoid arthritis
Dr. Karl Peggs
"One less known unknown?"
Starts: Mar 12, 2014 1:00:00 PM
The UCL Centre for Advanced Biomedical Imaging (CABI) has been awarded the unique opportunity to showcase their research at the UK’s most prestigious science exposition - The Royal Society Summer Science Exhibition. This was a very competitive process; 21 groups were selected from the UK, with CABI being the only group from UCL. More...
Published: Feb 21, 2014 9:51:48 AM
Professor Robert Kleta and team have discovered a new disease mechanism shedding light onto how the kidney works (Klootwijk et al., NEJM, 2014, 370, 129-138). As a trained paediatrician and geneticist he and Dr Detlef Bockenhauer from the Institute of Child Health together lead a competitive team based at Royal Free Hospital comprised out of renal doctors, geneticists, bioinformaticians, computer scientists, cell and molecular biologists and physiologists focused on the study of rare renal disease. They investigated a clinical problem called autosomal dominant renal Fanconi syndrome in paediatric and adult patients and thereby discovered a completely novel disease mechanism: they showed that aberrant trafficking of an enzyme can cause disease not by its absence in the organelle it was intended to be, but by disturbing function of the organelle it is wrongly routed to. They discovered that a mutation in a peroxisomal protein caused misrouting to the mitochondria and interfered with mitochondrial metabolism.
Prof. Leon Fine, Professor and Chair, Dept of Biomedical Sciences, Vice-Dean, Research and Graduate Research Education, Cedars-Sinai Medical Center, Los Angeles, USA, formely UCL, commented “The paper is a tour de force of clinical observation, interdisciplinary science, multi-institutional collaboration, genomics and cellular physiology, which has led to the determination of the cause of an inherited disease. A truly outstanding achievement.”
Published: Feb 21, 2014 8:39:25 AM
Very well done to Anisur Rahman for his place in the British Bangladeshi Power & Inspiration List 2014 and to Jayne Kavanagh who received the Provost's Award for Public Engagement. Jayne was nominated for this award for her leading role in creating and running the Beacon-funded 2013/14 project ‘Stories from the soul: doctors’ choices, women’s lives’. 'Stories from the soul’ includes three evenings of storytelling, music and discussion that bring together healthcare providers with members of the public to explore how doctors’ decisions affect women’s lives. More...
Published: Feb 20, 2014 11:51:52 AM
Professor Andrew K. Burroughs, a faculty of the UCL Institute for Liver and Digestive Health and consultant hepatologist at the Royal Free London, has recently been awarded the 2014 Distinguished Service Award of the International Liver Transplantation Society (ILTS) for his outstanding contribution to this field. Indeed, Professor Burroughs is one of the pioneers of transplant Hepatology and his research has greatly contributed to establishing the current management of liver transplantation. This represents a great honour for UK and European Hepatology.
During 2013, Professor Burroughs received two other major career awards: the Distinguished Career Award of the European Association for the Study of the Liver (EASL) and the highest honour from the British Society of Gastroenterology (BSG): the Sir Arthur Hurst Lecture.
In addition to his value as clinician and researcher, these awards were motivated by Professor Burroughs’ exceptional ability to mentor emerging talent in his field; indeed he has provided mentorship for an incredible number of UK and international hepatologists, in keeping with a tradition established at the Royal Free by his mentor Professor Dame Sheila Sherlock.
Published: Feb 18, 2014 12:35:43 PM
This year's Division of Medicine Research Retreat will take place on 6th June at the Renaissance London Heathrow Hotel, Bath Road, Hounslow TW6 2AQ.
Published: Feb 14, 2014 12:07:00 PM
Applications for the 2014 L’Oréal-UNESCO UK & Ireland
For Women in Science Fellowships now open
L’Oréal UK & Ireland, the UK National Commission for UNESCO and the Irish National Commission for UNESCO, with the support of the Royal Society have partnered together to provide a dedicated UK & Ireland For Women in Science fellowship programme for women scientists at post-doctoral level to enable and/or facilitate promising scientific research in the life and physical sciences.
Four Fellowships will be awarded in 2014 to outstanding female postdoctoral scientists to assist them with their research. The Fellowships, each worth £15,000 (equivalent Euros for candidates in Ireland), are tenable at any UK or Irish university or research institute to support a 12-month period of research.
The Fellowship money can be spent in any number of innovative ways to enable women scientists to further their careers and facilitate world class research - such as buying equipment, paying for childcare or funding travel costs to an overseas conference.
Applications open: Saturday 1st February
Application close: Friday 14th March
Shortlist published: Tuesday 3rd June
Awards ceremony: Thursday 19th June More...
Published: Feb 14, 2014 9:45:52 AM
Dr Alastair O’Brien has received £1.6 million from the Health Innovation Challenge Fund (joint Wellcome Trust & Department of Health) for ATTIRE (Albumin To prevenT Infection in chronic liveR failure). This is to fund a multi-centre clinical phase II and phase III trial at >15 sites that will examine whether administration of albumin to patients with liver failure in order to increase plasma levels to near normal will prevent hospital acquired infection. The clinical research network (LCRN) will fund the research nurse costs (>£1million). Over 100,000 patients are admitted to hospital every year with advanced liver cirrhosis and infection is their most common problem. Dr O’Brien and his team have shown that in these patients leukocyte function is markedly impaired by an up regulation of the hormone Prostaglandin E2 and infusion of albumin can reverse this process by binding and neutralising its effects. Albumin is widely considered to be beneficial in infection by hepatologists but until now there was no putative mechanism and therefore no consensus as to how to prescribe it. They wish to repurpose it as an immune restorative drug to improve leukocyte function in patients with advanced cirrhosis and therefore improve their ability to fight off infection. It is hoped to demonstrate that its use will lead to reduced nosocomial infection rates, mortality and length of stay and thereby reduce health care costs. More...
Published: Dec 19, 2013 3:39:05 PM
We are pleased to announce that Piumi Nikawala, a student of the Applied Biomedical Engineering Group, received the Gold CREST (CREactivity in Science and Technology) Award for her project on TIPS microspheres within the Nuffield Foundation Research Placement Programme. This is a nationally recognized scheme to reward Science & Technology project work.
Well done, Piumi!”
Published: Dec 11, 2013 10:05:41 AM
Lauren Bourke, a Grand Challenge PhD student in UCL’s Division of Medicine, has been awarded the Dean’s prize for her research into cardiac injury in systemic lupus erythematosus (SLE).
SLE is a systemic autoimmune condition which can affect multiple organs, although cardiovascular disease accounts for 25% of mortality. Lauren’s research has focused on ischaemic reperfusion (I/R) injury after myocardial infarction. This is a cause of up to half of cell death after MI, and occurs when hypoxic cells are reoxygenated. More specifically, she has found that hydroxychloroquine (a drug frequently used in the treatment of SLE) is protective against this kind of damage to cardiac muscle cells in vitro. More...
Published: Dec 9, 2013 2:39:23 PM
Page last modified on 22 mar 13 17:30