My main research interest lies in mechanical regulation of tissue growth and morphology during development and disease. During my PhD, I addressed the significance of mitotic spindle orientation in clear cell renal cell carcinoma (ccRCC) progression, in a context of loss of the von Hippel-Lindau (VHL) tumour suppressor protein. I provided direct evidence for a key role of VHL in mediating oriented cell division in the renal epithelium, emphasizing the importance of VHL as a controller of mitotic fidelity in vivo. Following my PhD, due to my interest in quantitative cell and tissue biology, I joined interdisciplinary laboratory of Dr. Mao to develop high-end cell biological quantitative approaches put in a physiological context. As a postdoc in Tissue Mechanics Laboratory of LMCB I investigate the coupling of mechanical and biochemical signalling in tissue morphology and growth control. I am using the Drosophila wing disc as the model tissue and employing a combinatorial biophysical, molecular, genetic and computational modelling approach. My research will lay the foundations for understanding of tissue growth control by mechanical forces - a finding that may ultimately lead to novel treatment strategies for cancer and wound healing.