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PREDICTS Project: Global Analysis Reveals Massive Biodiversity Losses

Thu, 21 May 2015 14:44:08 +0000

The changing climate is only one of a myriad of pressures faced by global biodiversity – we are also changing habitats and altering land-use on an unprecedented scale. The first global analysis published from the PREDICTS project reveals the striking global effect of land-use change on local biodiversity patterns, and highlights the importance of future […]

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Prof Jürg Bähler publishes lead article on Fission Yeast in Cell journal

1 November 2012

Quantitative Analysis of Fission Yeast Transcriptomes and Proteomes in Proliferating and Quiescent Cells

Samuel Marguerat, Alexander Schmidt, Sandra Codlin, Wei Chen, Ruedi Aebersold, and Jürg Bähler

This article reports cellular numbers for all RNAs and most proteins in proliferating and non-dividing cells of fission yeast. Most mRNAs are expressed at only 1-10 copies/cell, while corresponding proteins show greater abundance and range, from less than 100 to over 1 million copies/cell. Only a minority of long non-coding RNAs are expressed at >1 copy/cell. In the smaller non-dividing cells, the protein content changes substantially and RNA concentrations greatly decrease. These RNA and protein concentrations inform about cell regulation and function.

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