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Centre for Rheumatology and Bloomsbury Rheumatology

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Key Publications

  1. Giles IP, Pericleous C, Liu X, Ehsanullah J, Clarke L, Brogan P, Newton-West M, Swerlick R, Lambrianides A, Chen P, Latchman D, Isenberg D, Pierangeli S and Rahman A.  Thrombin binding predicts the effects of sequence changes in a human monoclonal antiphospholipid antibody on its in vivo biologic actions.  Journal of Immunology 2009; 182: 4836-43.
  2. Rahman A, Isenberg DA, Systemic Lupus Erythematosus - Mechanisms of disease.  New Eng J Med 2008; 358: 929-39.
  3. Blair PA, Yassin Norena L, Flores-Borja F, Rawlings DJ, Isenberg DA, Ehrenstein MR. Mauri C. CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients. Immunity 2010 32:1-12.
  4. Giles I, Lambrianides N, Latchman D, Chen P, Chukwuocha R, Isenberg D and Rahman A.  The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin.   Arthritis Research and Therapy 2005; 7: R47-R56.
  5. Nadkarni S, Mauri C, Ehrenstein MR. 2007. Anti-TNFα therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGFβ. J. Exp. Med. 204:33-9.
  6. Edwards JCW, Cambridge G.  B cell targeting in rheumatoid arthritis and other autoimmune diseases.  Nat Rev Immunol 2006; 6(5): 394-403.