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Psychiatry

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Pharmacogenetics in Mental Health

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Psychotropic medicines, including antidepressants, antipsychotics and antimanic drugs, can be very effective for many patients but can cause side effects. These may include weight gain, raised cholesterol, diabetes, sedation, movement disorders, raised prolactin, sexual dysfunction and osteoporosis. Many patients stop taking their medicine as a result of these side effects.

Genetic differences can influence the way people respond to their medicine. However, doctors do not usually consider their patients' genetics when they prescribe psychotropic medications. It is possible that genetic testing could help to improve the way we adjust the dose of these medications and help to reduce side effects.

We are conducting a pilot study to look at this. Patients who want to take part provide a blood or saliva sample for genetic testing. This will allow us to investigate the potential benefits of using genetic testing to guide treatment.

Elvira Bramon

IsabelleAZ

Johan_thygesen

Stella