The RADAR research study aims to test the effects of reducing and discontinuing antipsychotic medication in people with long-term schizophrenia and similar conditions. We want to know whether this approach can help people to function better in their daily lives. Some other evidence suggests this might be the case. We also want to know how it affects the chances of having a relapse. This study will be the first with this group of people that uses a gradual and flexible method of medication reduction, and that follows people up over the long-term.
Long-term psychotic conditions like schizophrenia and schizoaffective disorder are common and costly. The recommended treatment is long-term antipsychotic medication, but many people still find life difficult. Antipsychotics can also have dangerous and unpleasant side effects. Finding alternatives to long-term drug treatment is a priority for patients and services.