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Institute for the Physics of Living Systems

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Physics of multi-molecular assemblies and organelles

The Physics of compartment boundaries in biology image

Research Synopsis

The eminent physicist Wolfgang Pauli once quipped “God made the bulk; the surface was invented by the devil”. This is even more true in biology, where boundaries imply surfaces (or interfaces) and tend to be both incredibly important and yet remarkably elusive. We are interested in the physics that underpins the behaviour of these boundaries. This includes the dynamic and yet rather impermeable nature of cell membranes, force-dependent rearrangement of cell junctions during tissue growth, as well as various biological machines that operate at these boundaries, to our benefit or to our detriment.

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Bart Hoogenboom (Theme Lead)

Andela Saric (Theme Lead)