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"Creating Knowledge: sleep, novelty and memories", Lisa Genzel

28 January 2020, 1:00 pm–2:00 pm

Experimental Psychology Seminar

Experimental Psychology Seminar: "Creating Knowledge: sleep, novelty and memories.", Lisa Genzel (Radboud University)

This event is free.

Event Information

Open to

All

Availability

Yes

Cost

Free

Organiser

Antonietta Esposito

Location

Room 305
Department of Experimental Psychology
26 Bedford Way
London
WC1H 0DS
United Kingdom

Lisa Genzel, Donders Centre for Neuroscience (Radboud University)

Creating Knowledge: sleep, novelty and memories

Distinct forms of memory consolidation (cellular and systems) influence the persistence of spatial memory within the hippocampus (cellular) and following hippocampal-neocortical interactions (systems). Factors influencing these processes include: (1) novelty exposure that enhances the persistence of hippocampal traces via neuromodulation; and (2) sleep that aids systems consolidation and thus cortical memory. In a sequence of experiments, we could show that sleep leads to systems consolidation via learning-dependent cortical consolidation, which is counterbalanced by general downscaling. In contrast, novelty tags a memory to remain more hippocampal by increasing gene expression. Further, hippocampal and cortical memories differ in quality – episodic and semantic respectively – as well as properties such as resistance to interference. In this talk I will highlight how sleep and novelty can thus create knowledge networks from our every-day memories.