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LMCB - Laboratory for Molecular Cell Biology

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Research synopsis

 
My research interests are focused on the intersection between signalling and basic metabolism. My PhD focused on physiology and cardiometabolic changes due to acute and/or chronic stress and I have also led the research at LABEEST (Laboratory of Stress Study) into the evaluation of stress indicators in humans at Unicamp. In the Saiardi lab, I investigate the role played by inorganic polyphosphates (polyP) in mammalian cells. PolyP is a ubiquitous polymer of tens to hundreds of orthophosphate residues linked by high-energy phosphoanhydride bonds which have been found in all forms of life, from bacteria to animals. Whilst in prokaryotes and lower eukaryotes the presence of polyP and its synthesis are well-documented, in mammals, polyP is more elusive. My work focuses on increasing our knowledge of polyP including identifying its presence in mammals and understanding its production.
 

Biography

2021 | Research fellow at Saiardi lab – LMCB (UCL), UK
2020 | PhD in molecular and functional biology – University of Campinas (Unicamp), Brazil
2011 | Degree in Biological Sciences – University of Campinas (Unicamp), Brazil
 

Awards

2018 | Internship at Oregon Health & Sciences University (OHSU) by Graduate Committee BFM/IB/Unicamp, Brazil (3 months)
2016 | PhD fellowship by CAPES, Campinas, Brazil (4 years)
 

Funders

Medical Research Council

Research themes

Signaling pathways
Metabolism
Inorganic polyphosphates
Inositolphosphates
 

Technology

Light microscopy
Super-resolution microscopy
Translational research