Did Cro-Magnon 1 have neurofibromatosis type 1?

The Cro-Magnon 1 skeleton corresponds to a 28 000 BCE Homo sapiens male individual that was discovered in 1868 in a rock shelter in Les Eyzies, France.

Since its discovery, various diagnoses have been proposed with regards to a round polycyclic osteolytic lesion on the right frontal bone, measuring 37 mm x 27 mm (appendix): post-mortem alteration due to the soil, rickets, actinomycosis, and Langerhans cell histiocytosis.

Did Cro-Magnon 1 have neurofibromatosis type 1?

Philippe Charlier, Philippe Charlier, Nadia Benmoussa, Philippe Froesch, Isabelle Huynh-Charlier, Antoine Balzeau

DOI: 10.1016/S0140-6736(18)30495-1

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