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Cardiac MRI study recruiting patients with dilated cardiomyopathy

20 October 2023

Picture of a heart

Non-ischaemic dilated cardiomyopathy (DCM) is a common cardiac condition affecting 1 in 250 people, and patients are at increased risk of sudden cardiac death due to dangerous heart arrhythmia. Studies have shown that DCM patients with midwall septal fibrosis (MSF), a structural abnormality seen on cardiac MRI scans, confers an even greater risk of sudden cardiac death.  

In our BHF-funded research study “The arrhythmogenic potential of midwall septal fibrosis in non-ischaemic dilated cardiomyopathy, we are studying the hearts of DCM patients with and without MSF. Using novel ECG-imaging techniques and advanced cardiac MRI sequences, we hope to show how midwall septal fibrosis disrupts the heart’s electrical activity and can lead to dangerous heart rhythms.  

We are seeking patients with DCM to be part of our study, which involves a 2 hour visit to our phenotyping centre at UCL Bloomsbury Centre for Clinical Phenotyping in Lond. Participants will undergo several non-invasive tests, such as a cardiac MRI scan, an ECG-vest recording, basic measurements such as blood pressure, height & weight, and be asked to provide blood and urine samples.  If you are interested in taking part, please read the participant information sheet below and contact Dr Fiona Chan at f.chan@ucl.ac.uk.