To fulfil Antiresdev objectives, 12 work packages have been created - 10 of these are clinical- or science-based, one is for the management of the project and one is for the dissemination of the project findings.
WP 1 - Effect of minocycline administration on the emergence, prevalence and persistence of antibiotic-resistant bacteria in humans - Led by Helperby |
WP 2 - Effect of amoxicillin administration on the emergence, prevalence and persistence of antibiotic-resistant bacteria in humans - Led by Helperby |
WP 3 - Effect of ciprofloxacin administration on the emergence, prevalence and persistence of antibiotic-resistant bacteria in humans - Led by Karolinska Institutet |
WP 4 - Effect of clindamycin administration on the emergence, prevalence and persistence of antibiotic-resistant bacteria in humans - Led by Karolinska Institutet |
WP 5 - Resistome analysis and ecological consequences of antibiotic administration assessed by 454 pyrosequencing - Led by Academic Centre for Dentistry Amsterdam |
WP 6 - Identification of genes encoding antibiotic resistance in Gram-positive antibiotic-resistant isolates - Led by University of Berne |
WP 7 - Identification of genes encoding antibiotic resistance in Gram-negative antibiotic-resistant isolates - Veterinary Laboratories Agency |
WP 8 - Identification of antibiotic resistance determinants in pathogens of major clinical importance - Led by Robert-Bosch-Krankenhaus Zentrum für Diagnostische Medizin |
WP 9 - Characterisation of mobile genetic elements and resistance gene transfer - Led by University College London |
WP 10 Fitness costs associated with antibiotic resistance in clinically-important isolates - Led by University of Zurich |
WP 11 - Project management - Led by University College London |
WP 12 - Dissemination of findings - Led by University College London |